Menu

Bing Xia Lab Select Publications

  1. Foo TK, Tischkowitz M, Simhadri S, Boshari T, Zayed N, Burke KA, Berman SH, Blecua P, Riaz N, Huo Y, Ding YC, Neuhausen SL, Weigelt B, Reis-Filho JS, Foulkes WD and Xia B. (2017) Compromised BRCA1-PALB2 interaction is associated with breast cancer risk. Oncogene 36(29):4161-4170.
  2. Lu K, Alcivar AL, Ma J, Foo TK, Zywea S, Mahdi A, Huo Y, Kensler TW, Gatza ML and Xia B. (2017) NRF2 induction supporting breast cancer cell survival is enabled by oxidative stress-induced DPP3-KEAP1 interaction. Cancer Res 77(11):2881-2892.
  3. Anantha RW, Simhadri S, Foo TK, Miao S, Liu J, Shen Z, Ganesan S and Xia B. (2017) Functional and mutational landscapes of BRCA1 for homology-directed repair and therapy resistance. eLife 2017;10.7554/eLife.21350
  4. Buisson R, Niraj J, Rodrigue A, Ho CK, Kreuzer J, Foo TK, Hardy EJL, Dellaire G, Haas W, Xia B, Masson JY and Zou L. (2017) Coupling of Homologous Recombination and the Checkpoint by ATR. Mol Cell 65:336-346.
  5. Wu Q, Paul A, Su D, Mehmood S, Foo TK, Ochi T, Bunting EL, Xia B, Robinson CV, Wang B and Blundell TL. (2016) Structure of BRCA1-Abraxas complex reveals phosphorylation-dependent BRCT dimerization at DNA damage sites. Mol Cell 61:434-448.
  6. Orthwein A, Noordermeer SM, Wilson MD, Landry S, Enchev RI, Sherker A, Munro M, Pinder J, Salsman J, Dellaire G, Xia B, Peter M and Durocher D. (2015) A mechanism for the suppression of homologous recombination in G1 cells. Nature 528:422-6.
  7. Simhadri S, Peterson S, Patel D, Huo Y, Cai H, Miller S, Ludwig T, Ganesan S, Bhaumik M, Bunting S, Jasin M and Xia B. (2014) Male fertility defect associated with a disruption of BRCA1-PALB2 interaction in mice. J Biol Chem 289:24617-29.
  8. Nikkilä J, Parplys AC, Pylkäs K, Bose M, Huo Y, Borgmann K, Rapakko K, Nieminen P, Xia B, Pospiech H and Winqvist R. (2013) Heterozygous mutations in PALB2 cause DNA replication and damage response defects. Nat Commun 4:2578.
  9. Bowman-Colin C, Xia B, Bunting S, Klijn C, Drost R, Bouwman P, Fineman L, Chen X, Culhane AC, Cai H, Rodig SJ, Bronson RT, Jonkers J, Nussenzweig A, Kanellopoulou C and Livingston DM . (2013) Palb2 synergizes with Trp53 to suppress mammary tumor formation in a model of inherited breast cancer. Proc Natl Acad Sci USA 110:8632-7.
  10. Huo Y, Cai H, Teplova I, Bowman-Colin C, Chen G, Price S, Barnard N, Ganesan S, Karantza V, White E and Xia B. (2013) Autophagy opposes p53-mediated tumor barrier to facilitate tumorigenesis in a model of PALB2-associated hereditary breast cancer. Cancer Discov 3:894-907.
  11. Anantha RW, Alcivar AL, Ma J, Cai H, Simhadri S, Ule J, König J and Xia B. (2013) Requirement of heterogeneous nuclear ribonucleoprotein C for BRCA gene expression and homologous recombination. PloS ONE e61368
  12. Ma J, Cai H, Wu T, Sobhian B, Huo Y, Mehta M, Cheung KL, Ganesan S, Kong T, Zhang DD and Xia B. (2012) PALB2 interacts with KEAP1 to promote NRF2 nuclear accumulation and function. Mol Cell Biol 32:1506-17.

Click here to access a complete list of Bing Xia Lab publications: 
https://www.ncbi.nlm.nih.gov/myncbi/browse/collection/46023800/?sort=date&direction=descending

 

precision medicine at Rutgers Cancer Institute

 

 

 

ScreenNJ

 

 

Donate Now

 

 

 


 

 

 

 

Proud member of
Big Ten Cancer Research Consortium

 

 

Rutgers Health