Clinical Investigations Research Program

Program Leaders: Joseph Aisner, MD and Bruce Haffty, MD

Overall Goals:

The Clinical Investigations Program is structured to encourage and promote maximum scientific interactions among clinical, population and laboratory investigators, and provides a platform to facilitate rapid movement of laboratory discoveries into clinical trials.

Specific Aims:

  • To develop and validate therapeutic approaches targeting oncogenic tumor cell survival and proliferation mechanisms.
  • To develop therapeutic approaches that modulate cancer mechanisms of stress sensitivity and resistance.
  • To develop therapeutic approaches that target the microenvironment and immune surveillance.
  • To develop approaches to determine, calibrate, and validate biological activity and biomarkers of therapeutic approaches and preventive therapeutics.

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