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Chang S. Chan, PhD

Selected Publications

  1. Zhang C, Liu J, Wu R, Liang Y, Lin M, Liu J, Chan C.S., Hu W, Feng Z.  Tumor suppressor p53 negatively regulates glycolysis stimulated by hypoxia through its target RRAD. Oncotarget, 2014 June 26.
  2. Karsli-Uzunbas G, Guo JY, Price S, Teng X, Laddha SV, Khor S, Kalanny NY, Jacks T, Chan CS, Rabinowitz JD, White E.  Autophagy is required for glucose homeostasis and lung tumor maintenance.  Cancer Discov., 2014 May 29.
  3. Laddha SV, Ganesan S, Chan C.S.*, White E*.  Mutational landscape of the essential autophagy gene BECN1 in human cancers.  Mol Cancer Res., 12(4):485-90, 2014. *co-corresponding author.
  4. Sagne C, Marcel V, Bota M, Martel-Planche G, Nobrega A, Palmero E, Perriaud L, Boniol M, Vagner S, Cox D, Chan C.S., Mergny JL, Olivier M, Prolla P, Hall J, Hainaut P, Achatz M.  Age at cancer onset in germline TP53 mutation carriers: association with polymorphisms in predicted G-quadruplex structures. Carcinogenesis, 35(4):807-15, 2014.
  5. Hu W, Chan C.S., Zhang C., Sun Y., Song J.S., Levine A.J., Feng Z. Negative Regulation of Tumor Suppressor p53 by microRNA miR-504.  Molecular Cell, 38:689-699, 2010.
  6. Chan C.S., Song J.S.  CTCF Confines the Distal Action of Estrogen Receptor.  Cancer Research, 68(21): 9041-9049, 2008.
  7. Chan C.S., Elemento O., Tavazoie S. Revealing Post-transcriptional Regulatory Networks in Complex Genomes. PLoS Computational Biology, 1(7): e69, 2005.