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Gertrud (Trudi) Schupbach, PhD

Publications since 2011

McKoy, A. F. Chen, J. Schupbach, T. Hecht, M. H. Structure Activity Relationships for a Series of Compounds that Inhibit Aggregation of the Alzheimer's Peptide, Abeta42. Chem Biol Drug Des, 84:505-512, . (PMID: 24751138, PMCID: PMC4197064)

Li, W. Klovstad, M. Schupbach, T. Repression of Gurken translation by a meiotic checkpoint in Drosophila oogenesis is suppressed by a reduction in the dose of eIF1A. Development, 141:3910-3921, . (PMID: 25231760, PMCID: PMC4197705)

Devergne, O. Tsung, K. Barcelo, G. Schupbach, T. Polarized deposition of basement membrane proteins depends on Phosphatidylinositol synthase and the levels of Phosphatidylinositol 4,5-bisphosphate. Proc Natl Acad Sci U S A, 111:7689-7694, . (PMID: 24828534, PMCID: PMC4040573)

Domanitskaya, E. Anllo, L. Schupbach, T. Phantom, a cytochrome P450 enzyme essential for ecdysone biosynthesis, plays a critical role in the control of border cell migration in Drosophila. Dev Biol, 386:408-418, . (PMID: 24373956, PMCID: PMC4028970)

Fontenele, M. Lim, B. Oliveira, D. Buffolo, M. Perlman, D. H. Schupbach, T. Araujo, H. Calpain A modulates Toll responses by limited Cactus/IkappaB proteolysis. Mol Biol Cell, 24:2966-2980, . (PMID: 23864715, PMCID: PMC3771957)

Osterfield, M. Du, X. Schupbach, T. Wieschaus, E. Shvartsman, S. Y. Three-dimensional epithelial morphogenesis in the developing Drosophila egg. Dev Cell, 24:400-410, . (PMID: 23449472)

McKoy, A. F. Chen, J. Schupbach, T. Hecht, M. H. A novel inhibitor of amyloid beta (Abeta) peptide aggregation: from high throughput screening to efficacy in an animal model of Alzheimer disease. J Biol Chem, 287:38992-39000, . (PMID: 22992731, PMCID: PMC3493940)

Ferguson, S. B. Blundon, M. A. Klovstad, M. S. Schupbach, T. Modulation of gurken translation by insulin and TOR signaling in Drosophila. J Cell Sci, 125:1407-1419, . (PMID: 22328499, PMCID: PMC3336377)

Domanitskaya, E. Schupbach, T. CoREST acts as a positive regulator of Notch signaling in the follicle cells of Drosophila melanogaster. J Cell Sci, 125:399-410, . (PMID: 22331351, PMCID: PMC3283875)

Cheung, L. S. Schupbach, T. Shvartsman, S. Y. Pattern formation by receptor tyrosine kinases: analysis of the Gurken gradient in Drosophila oogenesis. Curr Opin Genet Dev, 21:719-725, . (PMID: 21862318)

Pane, A. Jiang, P. Zhao, D. Y. Singh, M. Schupbach, T. The Cutoff protein regulates piRNA cluster expression and piRNA production in the Drosophila germline. EMBO J, 30:4601-4615, . (PMID: 21952049, PMCID: PMC3243597)

Sun, Y. Yan, Y. Denef, N. Schupbach, T. Regulation of somatic myosin activity by protein phosphatase 1beta controls Drosophila oocyte polarization. Development, 138:1991-2001, . (PMID: 21490061, PMCID: PMC3082304)

Yan, Y. Denef, N. Tang, C. Schupbach, T. Drosophila PI4KIIIalpha is required in follicle cells for oocyte polarization and Hippo signaling. Development, 138:1697-1703, . (PMID: 21429988, PMCID: PMC3074446)