Researcher Profile

Bruce G. Haffty, MD

Co-Leader, Clinical Investigations Program; and Program Director, Department of Radiation Oncology Residency Training Program, Rutgers Robert Wood Johnson Medical School; Professor and Chair of Radiation Oncology, Rutgers New Jersey Medical School
Professor and Chair of Radiation Oncology
Robert Wood Johnson Medical School
Rutgers, The State University of New Jersey

Rutgers Cancer Institute of New Jersey
195 Little Albany Street
New Brunswick, NJ 08901-1914

Phone: (732) 235-5203
Email: bruce.haffty@rutgers.edu

Assistant: Jo-Ella McClinnon
(732) 235-6181
Email: joella.mcclinnon@rutgers.edu

Research Program Alignments

Membership Type: Full


Research Interests

  • Clinical, pathological and molecular factors, which may predict for outcome in patients treated with radiation therapy (primarily breast and head/neck cancer)
  • Evaluation of molecular and genetic markers that may be useful as prognostic factors and in guiding treatment decisions
  • Evaluation of long term outcome in women with breast cancer as a function of BRCA1/2 status.

Selected Publications

Parikh RR, Housman D, Yang Q, Toppmeyer D, Wilson LD, Haffty BG., Prognostic Value of Triple-Negative Phenotype at the Time of Locally Recurrent, Conservatively Treated Breast Cancer. Int J Radiat Oncol Biol Phys. 2008 Aug 1.

Yang Q, Moran MS, Haffty BG, Bcl-2 expression predicts local relapse for early stage breast cancer receiving conserving surgery and radiotherapy. Breast Cancer Res Treat. 2008 May 31

White JR, Halberg FE, Rabinovitch R, Green S, Haffty BG, Solin LJ, Strom EA, Taylor ME, Edge, SB, American College of Radiology appropriateness criteria on conservative surgery and radiation: stages I and II breast carcinoma. J Am Coll Radiol. 2008 Jun;5(6):701-13.

Haffty BG, Buchholz TA, McCormick B, Should intensity-modulated radiation therapy be the standard of care in the conservatively managed breast cancer patient? J Clin Oncol. 2008 May 1;26(13):2072-4. Epub 2008 Feb 19.

Haffty BG, Yang Q, Moran MS, Tan AR, Reiss M, Estrogen-dependent prognostic significance of cyclooxygenase-2 expression in early-stage invasive breast cancers treated with breast-conserving surgery and radiation. Int J Radiat Oncol Biol Phys. 2008 Jul 15;71(4):1006-13.

Choi DH, Cho DY, Lee MH, Park HS, Ahn SH, Son BH, Haffty BG., The CHEK21100delC mutation is not present in Korean patients with breast cancer cases tested for BRCA1 and BRCA2 mutation. Breast Cancer Res Treat. 2008 Jan 3.
 
Yue NJ , Kim S, Jabbour S, Narra V, Haffty BG., A strategy to objectively evaluate the necessity of correcting detected target deviations in image guided radiotherapy. Med Phys. 2007 Nov;34(11):4340-7.

Chang S, Zhou J, Liu Q, Metaxas DN, Haffty BG, Kim SN, Jabbour SJ, Yue NJ., Registration of lung tissue between fluoroscope and CT images: determination of beam gating parameters in radiotherapy. Med Image Comput Comput Assist Interv Int Conf Med Image Comput Comput Assist Interv. 2007;10(Pt 1):751-8.

Smith BD, Haffty BG, Smith GL, Hurria A, Buchholz TA, Gross CP., Use of postmastectomy radiotherapy in older women. Int J Radiat Oncol Biol Phys. 2008 May 1;71(1):98-106. Epub 2007 Nov 8.

Wilson LD, Yu JB, Haffty BG., National Residency Matching Program (NRMP)results for radiation oncology: 2007 update. Int J Radiat Oncol Biol Phys. 2007Oct 1;69(2):326-7.

Parikh RR, Yang Q, Higgins SA, Haffty BG., Outcomes in young women with breast cancer of triple-negative phenotype: the prognostic significance of CK19 expression. Int J Radiat Oncol Biol Phys. 2008 Jan 1;70(1):35-42. Epub 2007 Sep 12.

Yue NJ , Haffty BG, Yue J., On the assay of brachytherapy sources. Med Phys. 2007 Jun;34(6):1975-82.

Edvardsen H, Tefre T, Jansen L, Vu P, Haffty BG, Fosså SD, Kristensen VN, Børresen-Dale AL., Linkage disequilibrium pattern of the ATM gene in breast cancer patients and controls; association of SNPs and haplotypes to radio-sensitivity and post-lumpectomy local recurrence. Radiat Oncol. 2007 Jul 10; 2:25  

Ho AY, Fan G, Atencio DP, Green S, Formenti SC, Haffty BG, Iyengar P, Bernstein JL, Stock RG, Cesaretti JA, Rosenstein BS., Possession of ATM sequence variants as predictor for late normal tissue responses in breast cancer patients treated with radiotherapy. Int J Radiat Oncol Biol Phys. 2007 Nov 1;69(3):677-84. Epub 2007 May 22.

Goyal S, Kearney T, Haffty BG., Current application and research directions for partial-breast irradiation. Oncology (Williston Park ). 2007 Apr;21(4):449-61; discussion 461-2, 464, 470. Review.

The content for this Research Profile is maintained by Paul Novembre (novembre@cinj.rutgers.edu)