Researcher Profile

Ronald P. Hart, PhD

Professor of Cell Biology and Neuroscience
School of Arts and Sciences
Rutgers, The State University of New Jersey

Nelson Biology Laboratories
604 Allison Road, Room D251
Piscataway, NJ 08854

Phone: (732) 445-1783
Email: rhart@rci.rutgers.edu

Research Program Alignment

  • Non-Programmatically Aligned

Membership Type: Full


Research Interests

  • Development of induced pluripotent stem cells (iPSC) to study CNS disease
  • Role of microRNAs in cell differentiation and transformation
  • Identify specific mechanisms that contribute to stem cell differentiation to identify novel RNA targets for engineering therapeutic cells for transplant.

Selected Publications

Mahishi, L., D. Lynch, R.P. Hart, and R. Ratan (2012) MiR-886-3p levels are elevated in Friedreich ataxia. J Neurosci 32: 9369-73.

Moore, J.C., M.H. Sheldon and R.P. Hart (2012) Biobanking in the era of the stem cell: a technical and operational guide: The Use of iPSC to Study Genetic Diseases in Mental Health Disorders. Morgan-Claypool Publishers. DOI: 10.4199/C00059ED1V01Y201206SCB002

Li, J., J. Chen, C.L. Ricupero, R.P. Hart, M.S. Schwartz, A. Kusnecov and K. Herrup (2012) Nuclear accumulation of HDAC4 in ATM deficiency promotes neurodegeneration in ataxia telangiectasia. Nature Medicine. 18, 783–790.

Pichardo-Casas, I., L.A. Goff, M.R. Swerdel, A. Athie, J. Davila, M. Ramos-Brossier, M. Lapid-Volosin, W.J. Friedman, R.P. Hart and L. Vaca (2012) Expression profiling of synaptic microRNAs from the adult rat brain identifies regional differences and seizure-induced dynamic modulation, Brain Res 1436: 20-33.

Li, H., A.T. Hader, Y.R. Han, J.A. Wong, J. Babiarz, C.L. Ricupero, S.B. Godfrey, J.P. Corradi, M. Fennell, R.P. Hart, M.R. Plummer and M. Grumet (2011) Isolation of a novel rat neural progenitor clone that expresses Dlx family transcription factors and gives rise to functional GABAergic neurons in culture., Dev Neurobiol (doi: 10.1002/dneu.20977)

Ma, L., Y.M. Yu, Y. Guo, R.P. Hart and M. Schachner (2012) Cysteine- and glycine-rich protein 1a is involved in spinal cord regeneration in adult zebrafish, Eur J Neurosci 35: 353-65.

Yu, Y.M., K.M. Gibbs, J. Davila, N. Campbell, S. Sung, T.I. Todorova, S. Otsuka, H.E. Sabaawy, R.P. Hart and M. Schachner (2011) MicroRNA miR-133b is essential for functional recovery after spinal cord injury in adult zebrafish., Eur J Neurosci 33: 1587-97

Guo, Y., L. Ma, M. Cristofanilli, R.P. Hart, A. Hao and M. Schachner (2011) Transcription factor Sox11b is involved in spinal cord regeneration in adult zebrafish., Neuroscience 172: 329-41.

Camarillo, C., M. Swerdel and R.P. Hart (2011) Comparison of Microarray and Quantitative Real-Time PCR Methods for Measuring MicroRNA Levels in MSC Cultures., Methods Mol Biol 698: 419-429.

Wu, H., J. Tao, P. Chen, A. Shahab, W. Ge, R.P. Hart, X. Ruan, Y. Ruan and Y.E. Sun. Genome-wide Analysis Reveals MeCP2-dependent Regulation of MicroRNAs in a Mouse Model of Rett Syndrome. Proceedings of the National Academy of Sciences USA, 107: 18161-6. PMCID: PMC2964235

Moore, J.C., K. Atze, P. Yeung, A.J. Toro-Ramos, C. Camarillo, K. Thompson, C.L. Ricupero, M. Brenneman, R.I. Cohen and R.P. Hart (2010) Efficient, high-throughput transfection of human embryonic stem cells, Stem Cell Res Ther 1: 23 PMCID: PMC2941115

Lakshmipathy, U., J. Davila and R.P. Hart (2010) miRNA in pluripotent stem cells, Regen Med 5: 545-55. PMCID: PMC3077715

Bail, S., M. Swerdel, H. Liu, X. Jiao, L.A. Goff, R.P. Hart and M. Kiledjian (2010) Differential regulation of microRNA stability., RNA 16: 1032-9.

Moore, J.C., S. Sadowy, M. Alikani, A. Toro-Ramos, M.R. Swerdel, R. P. Hart, and R. I. Cohen. A high resolution molecular-based panel of assays for identification and characterization of human embryonic stem cell lines. Stem Cell Research, doi:10.1016/j.scr.2009.11.001.

Goff, L.A., J. Davila, M.R. Swerdel, J.C. Moore, R.I. Cohen, H. Wu, Y.E. Sun and R.P. Hart (2009) Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors., PLoS One 4: e7192.

The content for this Research Profile is maintained by Paul Novembre (novembre@cinj.rutgers.edu)