Cancer Metabolism and Growth Research Program

Program Leaders: Wei-Xing Zong, PhD and Eileen White, PhD


Overall Goals:

To determine how oncogenic signaling promotes tumor cell metabolism, growth, and survival, and alters tumor-host interaction to facilitate disease progression.  The ultimate goal is to identify new targets for drug development to improve cancer therapy.

Specific Aims:

  • To establish the role of cellular and mammalian metabolism in the control of tumor cell growth and survival and to modulate metabolic pathways to improve cancer therapy
  • To define the basic mechanisms of cell growth, proliferation, survival, stress adaptation, and metastasis in tumor cells
  • To identify the functional relationship between the tumor and host and how to harness host metabolism and immune response for anti-cancer therapy

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precision medicine at Rutgers Cancer Institute

 

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