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Daniel Hart, MD

Selected Publications

  1. Davila, J. L., Goff, L. A., Ricupero, C. L., Camarillo, C., Oni, E. N., Swerdel, M. R., Toro-Ramos, A. J., Li, J., & Hart, R. P. (2014). A Positive Feedback Mechanism That Regulates Expression of miR-9 during Neurogenesis. PloS one, 9, e94348.
  2. Ricupero, C. L., Swerdel, M. R., & Hart, R. P. (2013). Epigenome analysis of pluripotent stem cells. Methods in molecular biology (Clifton, N.J.), 997, 203-16.
  3. Li, J., Hart, R. P., Mallimo, E. M., Swerdel, M. R., Kusnecov, A. W., & Herrup, K. (2013). EZH2-mediated H3K27 trimethylation mediates neurodegeneration in ataxia-telangiectasia. Nature neuroscience, 16, 1745-53.
  4. Sauvageau, M., Goff, L. A., Lodato, S., Bonev, B., Groff, A. F., Gerhardinger, C., Sanchez-Gomez, D. B., Hacisuleyman, E., Li, E., Spence, M., Liapis, S. C., Mallard, W., Morse, M., Swerdel, M. R., D'Ecclessis, M. F., Moore, J. C., Lai, V., Gong, G., Yancopoulos, G. D., Frendewey, D., Kellis, M., Hart, R. P., Valenzuela, D. M., Arlotta, P., & Rinn, J. L. (2013). Multiple knockout mouse models reveal lincRNAs are required for life and brain development. eLife, 2, e01749.
  5. Deboer, E. M., Kraushar, M. L., Hart, R. P., & Rasin, M. R. (2013). Post-transcriptional regulatory elements and spatiotemporal specification of neocortical stem cells and projection neurons. Neuroscience 248C:499-528.
  6. Hannila, S. S., Siddiq, M. M., Carmel, J. B., Hou, J., Chaudhry, N., Bradley, P. M., Hilaire, M., Richman, E. L., Hart, R. P., & Filbin, M. T. (2013). Secretory Leukocyte Protease Inhibitor Reverses Inhibition by CNS Myelin, Promotes Regeneration in the Optic Nerve, and Suppresses Expression of the Transforming Growth Factor-β Signaling Protein Smad2. The Journal of neuroscience : the official journal of the Society for Neuroscience, 33, 5138-51.
  7. Komlos, D., Mann, K. D., Zhuo, Y., Ricupero, C. L., Hart, R. P., Liu, A. Y., & Firestein, B. L. (2013). Glutamate dehydrogenase 1 and SIRT4 regulate glial development. Glia, 61, 394-408.
  8. Mahishi, L., D. Lynch, R.P. Hart, and R. Ratan (2012) MiR-886-3p levels are elevated in Friedreich ataxia. J Neurosci 32: 9369-73.
  9. Moore, J.C., M.H. Sheldon and R.P. Hart (2012) Biobanking in the era of the stem cell: a technical and operational guide: The Use of iPSC to Study Genetic Diseases in Mental Health Disorders. Morgan-Claypool Publishers. DOI: 10.4199/C00059ED1V01Y201206SCB002
  10. Li, J., J. Chen, C.L. Ricupero, R.P. Hart, M.S. Schwartz, A. Kusnecov and K. Herrup (2012) Nuclear accumulation of HDAC4 in ATM deficiency promotes neurodegeneration in ataxia telangiectasia. Nature Medicine. 18, 783–790.
  11. Pichardo-Casas, I., L.A. Goff, M.R. Swerdel, A. Athie, J. Davila, M. Ramos-Brossier, M. Lapid-Volosin, W.J. Friedman, R.P. Hart and L. Vaca (2012) Expression profiling of synaptic microRNAs from the adult rat brain identifies regional differences and seizure-induced dynamic modulation, Brain Res 1436: 20-33.
  12. Li, H., A.T. Hader, Y.R. Han, J.A. Wong, J. Babiarz, C.L. Ricupero, S.B. Godfrey, J.P. Corradi, M. Fennell, R.P. Hart, M.R. Plummer and M. Grumet (2011) Isolation of a novel rat neural progenitor clone that expresses Dlx family transcription factors and gives rise to functional GABAergic neurons in culture., Dev Neurobiol (doi: 10.1002/dneu.20977)
  13. Ma, L., Y.M. Yu, Y. Guo, R.P. Hart and M. Schachner (2012) Cysteine- and glycine-rich protein 1a is involved in spinal cord regeneration in adult zebrafish, Eur J Neurosci 35: 353-65.
  14. Yu, Y.M., K.M. Gibbs, J. Davila, N. Campbell, S. Sung, T.I. Todorova, S. Otsuka, H.E. Sabaawy, R.P. Hart and M. Schachner (2011) MicroRNA miR-133b is essential for functional recovery after spinal cord injury in adult zebrafish., Eur J Neurosci 33: 1587-97
  15. Guo, Y., L. Ma, M. Cristofanilli, R.P. Hart, A. Hao and M. Schachner (2011) Transcription factor Sox11b is involved in spinal cord regeneration in adult zebrafish., Neuroscience 172: 329-41.
  16. Camarillo, C., M. Swerdel and R.P. Hart (2011) Comparison of Microarray and Quantitative Real-Time PCR Methods for Measuring MicroRNA Levels in MSC Cultures., Methods Mol Biol 698: 419-429.
  17. Wu, H., J. Tao, P. Chen, A. Shahab, W. Ge, R.P. Hart, X. Ruan, Y. Ruan and Y.E. Sun. Genome-wide Analysis Reveals MeCP2-dependent Regulation of MicroRNAs in a Mouse Model of Rett Syndrome. Proceedings of the National Academy of Sciences USA, 107: 18161-6. PMCID: PMC2964235
  18. Moore, J.C., K. Atze, P. Yeung, A.J. Toro-Ramos, C. Camarillo, K. Thompson, C.L. Ricupero, M. Brenneman, R.I. Cohen and R.P. Hart (2010) Efficient, high-throughput transfection of human embryonic stem cells, Stem Cell Res Ther 1: 23 PMCID: PMC2941115
  19. Lakshmipathy, U., J. Davila and R.P. Hart (2010) miRNA in pluripotent stem cells, Regen Med 5: 545-55. PMCID: PMC3077715
  20. Bail, S., M. Swerdel, H. Liu, X. Jiao, L.A. Goff, R.P. Hart and M. Kiledjian (2010) Differential regulation of microRNA stability., RNA 16: 1032-9.
  21. Moore, J.C., S. Sadowy, M. Alikani, A. Toro-Ramos, M.R. Swerdel, R. P. Hart, and R. I. Cohen. A high resolution molecular-based panel of assays for identification and characterization of human embryonic stem cell lines. Stem Cell Research, doi:10.1016/j.scr.2009.11.001.
  22. Goff, L.A., J. Davila, M.R. Swerdel, J.C. Moore, R.I. Cohen, H. Wu, Y.E. Sun and R.P. Hart (2009) Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors., PLoS One 4: e7192.