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Leonid Kagan, PhD

Publications since 2011

Ginosar, Y. Haroutounian, S. Kagan, L. Naveh, M. Aharon, A. Davidson, E. M. Proliposomal Ropivacaine Oil: Pharmacokinetic and Pharmacodynamic Data After Subcutaneous Administration in Volunteers. Anesth Analg, In process, . (PMID: 27057798)

Davidson, E. M. Haroutounian, S. Kagan, L. Naveh, M. Aharon, A. Ginosar, Y. A Novel Proliposomal Ropivacaine Oil: Pharmacokinetic-Pharmacodynamic Studies After Subcutaneous Administration in Pigs. Anesth Analg, In process, . (PMID: 27057797)

Brunetti, L. Sanchez-Catanese, B. Kagan, L. Wen, X. Liu, M. Buckley, B. Luyendyk, J. P. Aleksunes, L. M. Evaluation of the chromogenic anti-factor IIa assay to assess dabigatran exposure in geriatric patients with atrial fibrillation in an outpatient setting. Thromb J, 14:10, . (PMID: 27158246, PMCID: PMC4858862)

Brunetti, L. Kagan, L. Forrester, G. Aleksunes, L. M. Lin, H. Buyske, S. Nahass, R. G. Cefoxitin Plasma and Subcutaneous Adipose Tissue Concentration in Patients Undergoing Sleeve Gastrectomy. Clin Ther, In process, . (PMID: 26686826)

Kagan, L. Zhao, J. Mager, D. E. Interspecies Pharmacokinetic Modeling of Subcutaneous Absorption of Rituximab in Mice and Rats. Pharm Res, 31:3265-3273, . (PMID: 24852895)

Kagan, L. Pharmacokinetic Modeling of the Subcutaneous Absorption of Therapeutic Proteins. Drug Metab Dispos, 42:1890-1905, . (PMID: 25122564)

Passey, C. Kimko, H. Nandy, P. Kagan, L. Osteoarthritis disease progression model using six year follow-up data from the Osteoarthritis Initiative. J Clin Pharmacol, In process, . (PMID: 25212288)

Chen, T. Kagan, L. Mager, D. E. Population Pharmacodynamic Modeling of Exenatide After 2-Week Treatment in STZ/NA Diabetic Rats. J Pharm Sci, 102:3844-3851, . (PMID: 23897494)

Haroutiunian, S. Kagan, L. Yifrach-Damari, I. Davidson, E. Ratz, Y. Hoffman, A. Enhanced antinociceptive efficacy of epidural compared with i.v. methadone in a rat model of thermal nociception. Br J Anaesth, In process, . (PMID: 23842610)

Kagan, L. Gershkovich, P. Wasan, K. M. Mager, D. E. Dual Physiologically Based Pharmacokinetic Model of Liposomal and Nonliposomal Amphotericin B Disposition. Pharm Res, In process, . (PMID: 23793994)

Chen, T. Mager, D. E. Kagan, L. Interspecies modeling and prediction of human exenatide pharmacokinetics. Pharm Res, 30:751-760, . (PMID: 23229855, PMCID: PMC3732180)

Kagan, L. Mager, D. E. Mechanisms of subcutaneous absorption of rituximab in rats. Drug Metab Dispos, 41:248-255, . (PMID: 23129212)

Kagan, L. Turner, M. R. Balu-Iyer, S. V. Mager, D. E. Subcutaneous absorption of monoclonal antibodies: role of dose, site of injection, and injection volume on rituximab pharmacokinetics in rats. Pharm Res, 29:490-499, . (PMID: 21887597)

Horwitz, E. Kagan, L. Avni-Magen, N. Daryi, D. Gati, I. Hoffman, A. Friedman, M. Lavy, E. A novel subcutaneous controlled-release amoxicillin degradable implant for extended-interval administration in veterinary medicine. J Vet Pharmacol Ther, 34:494-498, . (PMID: 21198679)

Horwitz, E. Kagan, L. Chamisha, Y. Gati, I. Hoffman, A. Friedman, M. Lavy, E. Novel gastroretentive controlled-release drug delivery system for amoxicillin therapy in veterinary medicine. J Vet Pharmacol Ther, 34:487-493, . (PMID: 21198678)

Kagan, L. Gershkovich, P. Wasan, K. M. Mager, D. E. Physiologically based pharmacokinetic model of amphotericin B disposition in rats following administration of deoxycholate formulation (Fungizone(R)): pooled analysis of published data. AAPS J, 13:255-264, . (PMID: 21431453, PMCID: PMC3085707)