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Bin Tian, PhD

Publications since 2011

Di Giammartino, D. C. Li, W. Ogami, K. Yashinskie, J. J. Hoque, M. Tian, B. Manley, J. L. RBBP6 isoforms regulate the human polyadenylation machinery and modulate expression of mRNAs with AU-rich 3' UTRs. Genes Dev, 28:2248-2260, . (PMID: 25319826, PMCID: PMC4201286)

Kurosaki, T. Li, W. Hoque, M. Popp, M. W. Ermolenko, D. N. Tian, B. Maquat, L. E. A post-translational regulatory switch on UPF1 controls targeted mRNA degradation. Genes Dev, 28:1900-1916, . (PMID: 25184677, PMCID: PMC4197951)

Rosonina, E. Yurko, N. Li, W. Hoque, M. Tian, B. Manley, J. L. Threonine-4 of the budding yeast RNAP II CTD couples transcription with Htz1-mediated chromatin remodeling. Proc Natl Acad Sci U S A, In process, . (PMID: 25071213)

Zheng, D. Tian, B. Sizing up the poly(A) tail: insights from deep sequencing. Trends Biochem Sci, 39:255-257, . (PMID: 24751511)

Hsin, J. P. Li, W. Hoque, M. Tian, B. Manley, J. L. RNAP II CTD tyrosine 1 performs diverse functions in vertebrate cells. Elife (Cambridge), 3:e02112, . (PMID: 24842995, PMCID: PMC4042873)

Hoque, M. Li, W. Tian, B. Accurate mapping of cleavage and polyadenylation sites by 3' region extraction and deep sequencing. Methods Mol Biol, 1125:119-129, . (PMID: 24590784)

Luo, W. Ji, Z. Pan, Z. You, B. Hoque, M. Li, W. Gunderson, S. I. Tian, B. The conserved intronic cleavage and polyadenylation site of CstF-77 gene imparts control of 3' end processing activity through feedback autoregulation and by U1 snRNP. PLoS Genet, 9:e1003613, . (PMID: 23874216, PMCID: PMC3708835)

Elbarbary, R. A. Li, W. Tian, B. Maquat, L. E. STAU1 binding 3' UTR IRAlus complements nuclear retention to protect cells from PKR-mediated translational shutdown. Genes Dev, 27:1495-1510, . (PMID: 23824540, PMCID: PMC3713430)

Tian, B. Manley, J. L. Alternative cleavage and polyadenylation: the long and short of it. Trends Biochem Sci, 38:312-320, . (PMID: 23632313, PMCID: PMC3800139)

Devany, E. Zhang, X. Park, J. Y. Tian, B. Kleiman, F. E. Positive and negative feedback loops in the p53 and mRNA 3' processing pathways. Proc Natl Acad Sci U S A, 110:3351-3356, . (PMID: 23401530, PMCID: PMC3587245)

Matsushima, S. Kuroda, J. Ago, T. Zhai, P. Park, J. Y. Xie, L. H. Tian, B. Sadoshima, J. Increased oxidative stress in the nucleus caused by Nox4 mediates oxidation of HDAC4 and cardiac hypertrophy. Circ Res, 112:651-663, . (PMID: 23271793, PMCID: PMC3574183)

Hoque, M. Ji, Z. Zheng, D. Luo, W. Li, W. You, B. Park, J. Y. Yehia, G. Tian, B. Analysis of alternative cleavage and polyadenylation by 3' region extraction and deep sequencing. Nat Methods, 10:133-139, . (PMID: 23241633, PMCID: PMC3560312)

Bravo, C. Kudej, R. K. Yuan, C. Yoon, S. Ge, H. Park, J. Y. Tian, B. Stanley, W. C. Vatner, S. F. Vatner, D. E. Yan, L. Metabolomic analysis of two different models of delayed preconditioning. J Mol Cell Cardiol, 55:19-26, . (PMID: 23127662)

Prasad, M. K. Bhalla, K. Pan, Z. H. O'Connell, J. R. Weder, A. B. Chakravarti, A. Tian, B. Chang, Y. P. A polymorphic 3'UTR element in ATP1B1 regulates alternative polyadenylation and is associated with blood pressure. PLoS One, 8:e76290, . (PMID: 24098465, PMCID: PMC3788127)

Yan, L. Park, J. Y. Dillinger, J. G. De Lorenzo, M. S. Yuan, C. Lai, L. Wang, C. Ho, D. Tian, B. Stanley, W. C. Auwerx, J. Vatner, D. E. Vatner, S. F. Common mechanisms for calorie restriction and adenylyl cyclase type 5 knockout models of longevity. Aging Cell, 11:1110-1120, . (PMID: 23020244, PMCID: PMC3646327)

Yin, J. W. Liang, Y. Park, J. Y. Chen, D. Yao, X. Xiao, Q. Liu, Z. Jiang, B. Fu, Y. Bao, M. Huang, Y. Liu, Y. Yan, J. Zhu, M. S. Yang, Z. Gao, P. Tian, B. Li, D. Wang, G. Mediator MED23 plays opposing roles in directing smooth muscle cell and adipocyte differentiation. Genes Dev, 26:2192-2205, . (PMID: 22972934, PMCID: PMC3465740)

Neff, A. T. Lee, J. Y. Wilusz, J. Tian, B. Wilusz, C. J. Global analysis reveals multiple pathways for unique regulation of mRNA decay in induced pluripotent stem cells. Genome Res, 22:1457-1467, . (PMID: 22534399, PMCID: PMC3409259)

Henriques, T. Ji, Z. Tan-Wong, S. M. Carmo, A. M. Tian, B. Proudfoot, N. J. Moreira, A. Transcription termination between polo and snap, two closely spaced tandem genes of D. melanogaster. Transcription, 3:198-212, . (PMID: 22992452, PMCID: PMC3654770)

Haenni, S. Ji, Z. Hoque, M. Rust, N. Sharpe, H. Eberhard, R. Browne, C. Hengartner, M. O. Mellor, J. Tian, B. Furger, A. Analysis of C. elegans intestinal gene expression and polyadenylation by fluorescence-activated nuclei sorting and 3'-end-seq. Nucleic Acids Res, 40:6304-6318, . (PMID: 22467213, PMCID: PMC3401467)

Xie, L. H. Shanmugam, M. Park, J. Y. Zhao, Z. Wen, H. Tian, B. Periasamy, M. Babu, G. J. Ablation of sarcolipin results in atrial remodeling. Am J Physiol Cell Physiol, 302:C1762-C1771, . (PMID: 22496245, PMCID: PMC3378074)

Tian, B. Graber, J. H. Signals for pre-mRNA cleavage and polyadenylation. Wiley Interdiscip Rev RNA, 3:385-396, . (PMID: 22012871)

Zhao, X. Park, J. Ho, D. Gao, S. Yan, L. Ge, H. Iismaa, S. Lin, L. Tian, B. Vatner, D. E. Graham, R. M. Vatner, S. F. Cardiomyocyte overexpression of the alpha1A-adrenergic receptor in the rat phenocopies second but not first window preconditioning. Am J Physiol Heart Circ Physiol, 302:H1614-H1624, . (PMID: 22307672, PMCID: PMC3330800)

Oka, S. Zhai, P. Alcendor, R. Park, J. Y. Tian, B. Sadoshima, J. Suppression of ERR targets by a PPARalpha/Sirt1 complex in the failing heart. Cell Cycle, 11:856-864, . (PMID: 22333581, PMCID: PMC3323793)

Huang, Y. Li, W. Yao, X. Lin, Q. J. Yin, J. W. Liang, Y. Heiner, M. Tian, B. Hui, J. Wang, G. Mediator complex regulates alternative mRNA processing via the MED23 subunit. Mol Cell, 45:459-469, . (PMID: 22264826, PMCID: PMC3288850)

Freed-Pastor, W. A. Mizuno, H. Zhao, X. Langerod, A. Moon, S. H. Rodriguez-Barrueco, R. Barsotti, A. Chicas, A. Li, W. Polotskaia, A. Bissell, M. J. Osborne, T. F. Tian, B. Lowe, S. W. Silva, J. M. Borresen-Dale, A. L. Levine, A. J. Bargonetti, J. Prives, C. Mutant p53 disrupts mammary tissue architecture via the mevalonate pathway. Cell, 148:244-258, . (PMID: 22265415, PMCID: PMC3511889)

Li, W. Laishram, R. S. Ji, Z. Barlow, C. A. Tian, B. Anderson, R. A. Star-PAP control of BIK expression and apoptosis is regulated by nuclear PIPKIalpha and PKCdelta signaling. Mol Cell, 45:25-37, . (PMID: 22244330, PMCID: PMC3268557)

Li, W. Yeh, H. J. Shankarling, G. S. Ji, Z. Tian, B. MacDonald, C. C. The tauCstF-64 polyadenylation protein controls genome expression in testis. PLoS One, 7:e48373, . (PMID: 23110235, PMCID: PMC3482194)

Lee, J. E. Lee, J. Y. Trembly, J. Wilusz, J. Tian, B. Wilusz, C. J. The PARN deadenylase targets a discrete set of mRNAs for decay and regulates cell motility in mouse myoblasts. PLoS Genet, 8:e1002901, . (PMID: 22956911, PMCID: PMC3431312)

Oka, S. Alcendor, R. Zhai, P. Park, J. Y. Shao, D. Cho, J. Yamamoto, T. Tian, B. Sadoshima, J. PPARalpha-Sirt1 complex mediates cardiac hypertrophy and failure through suppression of the ERR transcriptional pathway. Cell Metab, 14:598-611, . (PMID: 22055503, PMCID: PMC3217210)

Qiu, H. Lizano, P. Laure, L. Sui, X. Rashed, E. Park, J. Y. Hong, C. Gao, S. Holle, E. Morin, D. Dhar, S. K. Wagner, T. Berdeaux, A. Tian, B. Vatner, S. F. Depre, C. H11 kinase/heat shock protein 22 deletion impairs both nuclear and mitochondrial functions of STAT3 and accelerates the transition into heart failure on cardiac overload. Circulation, 124:406-415, . (PMID: 21747053, PMCID: PMC3369833)

Usui, S. Maejima, Y. Pain, J. Hong, C. Cho, J. Park, J. Y. Zablocki, D. Tian, B. Glass, D. J. Sadoshima, J. Endogenous muscle atrophy F-box mediates pressure overload-induced cardiac hypertrophy through regulation of nuclear factor-kappaB. Circ Res, 109:161-171, . (PMID: 21617130, PMCID: PMC3257317)

Parrott, A. M. Tsai, M. Batchu, P. Ryan, K. Ozer, H. L. Tian, B. Mathews, M. B. The evolution and expression of the snaR family of small non-coding RNAs. Nucleic Acids Res, 39:1485-1500, . (PMID: 20935053, PMCID: PMC3045588)

Ji, Z. Luo, W. Li, W. Hoque, M. Pan, Z. Zhao, Y. Tian, B. Transcriptional activity regulates alternative cleavage and polyadenylation. Mol Syst Biol, 7:534, . (PMID: 21952137, PMCID: PMC3202805)

Park, J. Y. Li, W. Zheng, D. Zhai, P. Zhao, Y. Matsuda, T. Vatner, S. F. Sadoshima, J. Tian, B. Comparative analysis of mRNA isoform expression in cardiac hypertrophy and development reveals multiple post-transcriptional regulatory modules. PLoS One, 6:e22391, . (PMID: 21799842, PMCID: PMC3142162)

Zhao, Q. Beck, A. J. Vitale, J. M. Schneider, J. S. Gao, S. Chang, C. Elson, G. Leibovich, S. J. Park, J. Y. Tian, B. Nam, H. S. Fraidenraich, D. Developmental ablation of Id1 and Id3 genes in the vasculature leads to postnatal cardiac phenotypes. Dev Biol, 349:53-64, . (PMID: 20937270, PMCID: PMC2993814)