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Fumio Matsumura, PhD

Selected Publications

  1. Yamashiro, S. Yamakita Y., Ishikawa, R., and Matsumura, F.  Mitosis-specific phosphorylation causes 83kDa nonmuscle caldesmon to dissociate from microfilaments.  Nature  344, 675-678, 1990. 
  2. Yamashiro, S. and Yamakita, Y., Hosoya, H., and Matsumura F.  Phosphorylation of nonmuscle caldesmon by p34cdc2 kinase during mitosis.  Nature 349, 169-172, 1991.
  3. Mosialos, G., Birkenbach, M., Ayehunie, S., Matsumura, F., Pinkus G. S., Kieff, E., and Langhoff, E.  Circulating human dendritic cells differentially express high levels of a 55-kd actin bundling protein.  American J. Pathology.  148: 593-600, 1996
  4. Ono, S., Yamakita, S., S. Yamashiro†, P. T. Matsudaira, J. R. Gnarra, T. Obinata, and Matsumura, F.  Identification of an Actin Binding Region and a PKC Phosphorylation Site on Human Fascin.  J. Biol. Chem. 272:2527-2533, 1997
  5. Totsukawa G., Wu, Y., Sasaki, Y., Hartshorne, D. J., Yamakita Y., Yamashiro, S. and Matsumura, F.  Distinct roles of MLCK and ROCK in the regulation of membrane protrusions and focal adhesion dynamics during cell migration of fibroblasts.  J. Cell Biol. 164: 427-439. 2004. PMCID: PMC2172229
  6. Yamashiro, S., Yamakita, Y., Totsukawa, G., Goto, H., Kaibuchi, K., Ito, M., Hartshorne, D. and Matsumura, F.   Myosin phosphatase targeting subunit1 regulates mitosis by antagonizing polo-like kinase1.  Dev. Cell 14:787-797. 2008. PMCID: PMC2680213
  7. Siedu, M., A D. Wu, F. Matsumura, and Q. Wei  Centrosome/spindle pole-associated protein (CSPP) regulates cytokinesis via promoting the recruitment of MyoGEF to the central spindle. Molecular Biology of Cell, 20(5):1428-40. 2009. PMCID: PMC2649278
  8. Yamakita, Y., Matsumura, F., and Yamashiro, S. Fascin1 is dispensable for mouse development but is favorable for neonatal survival. Cell Motility and the Cytoskeleton, 66(8):524-534. 2009. PMCID: PMC2738588
  9. Sedeh RS, Fedorov AA, Fedorov EV, Ono S, Matsumura F, Almo SC, and Bathe M. Structure, Evolutionary Conservation, and Conformational Dynamics of Homo sapiens Fascin-1, an F-actin Crosslinking Protein. J. Mol. Biol. 2010. 400:589-604
  10. Pal, D., D. Wu, A. Haruta, F. Matsumura, and Q. Wei. Role of a novel coiled-coil domain-containing protein CCDC69 in regulating central spindle assembly. Cell Cycle. 9:4117-29. 2010. PMCID: PMC3055196
  11. Yamakita, Y., F. Matsumura, M.W. Lipscomb, P.C. Chou, G. Werlen, J.K. Burkhardt, and S. Yamashiro. Fascin1 Promotes Cell Migration of Mature Dendritic Cells. J Immunol. 186: 2850-9. 2011. PMCID: PMC2738588
  12. Matsumura, F., Y. Yamakita, and S. Yamashiro. Myosin phosphatase targeting subunit1 controls chromatid segregation. J Biol Chem. 2011. 286: 10825-10833. 2011. PMCID: PMC3060533
  13. Matsumura, F., Yamakita, Y., and Yamashiro, S., Myosin light chain kinases and phosphatase in mitosis and cytokinesis. Arch Biochem Biophys, 510:76-82.  2011
  14. Matsumura, F., Y. Yamakita, V. Starovoytov, and Yamashiro. S., Fascin confers resistance to Listeria infection in dendritic cells. Journal of Immunology, 191:6156-64. 2013. PMCID:3858451
  15. Wu, D., Asiedu, M, Matsumura, F., Wei, Q., Phosphorylation of myosin II-interacting guanine nucleotide exchange factor (MyoGEF) at Threonine 544 by Aurora B kinase promotes the binding of Polo-like kinase 1 to MyoGEF. J. Biol. Chem. 289:7142-50. 2014. PMCID: PMC3945374