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Alexey G. Ryazanov, PhD

Publications since 2011

von Hoven, G. Neukirch, C. Meyenburg, M. Fuser, S. Petrivna, M. B. Rivas, A. J. Ryazanov, A. Kaufman, R. J. Aroian, R. V. Husmann, M. eIF2alpha Confers Cellular Tolerance to S. aureus alpha-Toxin. Front Immunol, 6:383, . (PMID: 26284068, PMCID: PMC4515601)

Nikonorova, I. A. Kornakov, N. V. Dmitriev, S. E. Vassilenko, K. S. Ryazanov, A. G. Identification of a Mg2+-sensitive ORF in the 5'-leader of TRPM7 magnesium channel mRNA. Nucleic Acids Res, 42:12779-12788, . (PMID: 25326319, PMCID: PMC4227784)

Faller, W. J. Jackson, T. J. Knight, J. R. Ridgway, R. A. Jamieson, T. Karim, S. A. Jones, C. Radulescu, S. Huels, D. J. Myant, K. B. Dudek, K. M. Casey, H. A. Scopelliti, A. Cordero, J. B. Vidal, M. Pende, M. Ryazanov, A. G. Sonenberg, N. Meyuhas, O. Hall, M. N. Bushell, M. Willis, A. E. Sansom, O. J. mTORC1-mediated translational elongation limits intestinal tumour initiation and growth. Nature, In process, . (PMID: 25383520)

Faller, W. Jackson, T. Ridgway, R. Knight, J. Jamieson, T. Pende, M. Ryazanov, A. Sonenberg, N. Meyuhas, O. Bushell, M. Hall, M. Willis, A. Sansom, O. PWE-021 Mtorc1 Mediated Translational Elongation Is Limiting For Intestinal Tumour Initiation And Growth. Gut, 63:A130-A131, . (PMID: 25021501)

Chu, H. P. Liao, Y. Novak, J. S. Hu, Z. Merkin, J. J. Shymkiv, Y. Braeckman, B. P. Dorovkov, M. V. Nguyen, A. Clifford, P. M. Nagele, R. G. Harrison, D. E. Ellis, R. E. Ryazanov, A. G. Germline Quality Control: eEF2K Stands Guard to Eliminate Defective Oocytes. Dev Cell, 28:561-572, . (PMID: 24582807)

Ryazanova, L. V. Hu, Z. Suzuki, S. Chubanov, V. Fleig, A. Ryazanov, A. G. Elucidating the role of the TRPM7 alpha-kinase: TRPM7 kinase inactivation leads to magnesium deprivation resistance phenotype in mice. Sci Rep, 4:7599, . (PMID: 25534891)

Nosyreva, E. Szabla, K. Autry, A. E. Ryazanov, A. G. Monteggia, L. M. Kavalali, E. T. Acute suppression of spontaneous neurotransmission drives synaptic potentiation. J Neurosci, 33:6990-7002, . (PMID: 23595756, PMCID: PMC3661220)

Hizli, A. A. Chi, Y. Swanger, J. Carter, J. H. Liao, Y. Welcker, M. Ryazanov, A. G. Clurman, B. E. Phosphorylation of Eukaryotic Elongation Factor 2 (eEF2) by Cyclin A-Cyclin-Dependent Kinase 2 Regulates Its Inhibition by eEF2 Kinase. Mol Cell Biol, 33:596-604, . (PMID: 23184662, PMCID: PMC3554216)

Newman, R. H. Hu, J. Rho, H. S. Xie, Z. Woodard, C. Neiswinger, J. Cooper, C. Shirley, M. Clark, H. M. Hu, S. Hwang, W. Jeong, J. S. Wu, G. Lin, J. Gao, X. Ni, Q. Goel, R. Xia, S. Ji, H. Dalby, K. N. Birnbaum, M. J. Cole, P. A. Knapp, S. Ryazanov, A. G. Zack, D. J. Blackshaw, S. Pawson, T. Gingras, A. C. Desiderio, S. Pandey, A. Turk, B. E. Zhang, J. Zhu, H. Qian, J. Construction of human activity-based phosphorylation networks. Mol Syst Biol, 9:655, . (PMID: 23549483, PMCID: PMC3658267)

Abramczyk, O. Tavares, C. D. Devkota, A. K. Ryazanov, A. G. Turk, B. E. Riggs, A. F. Ozpolat, B. Dalby, K. N. Purification and characterization of tagless recombinant human elongation factor 2 kinase (eEF-2K) expressed in Escherichia coli. Protein Expr Purif, 79:237-244, . (PMID: 21605678, PMCID: PMC3389548)

Bewley, M. A. Pham, T. K. Marriott, H. M. Noirel, J. Chu, H. P. Ow, S. Y. Ryazanov, A. G. Read, R. C. Whyte, M. K. Chain, B. Wright, P. C. Dockrell, D. H. Proteomic evaluation and validation of cathepsin D regulated proteins in macrophages exposed to Streptococcus pneumoniae. Mol Cell Proteomics, 10:M111.008193, . (PMID: 21474794, PMCID: PMC3108842)

Dorovkov, M. V. Kostyukova, A. S. Ryazanov, A. G. Phosphorylation of annexin A1 by TRPM7 kinase: a switch regulating the induction of an alpha-helix. Biochemistry, 50:2187-2193, . (PMID: 21280599, PMCID: PMC3062375)

Perraud, A. L. Zhao, X. Ryazanov, A. G. Schmitz, C. The channel-kinase TRPM7 regulates phosphorylation of the translational factor eEF2 via eEF2-k. Cell Signal, 23:586-593, . (PMID: 21112387, PMCID: PMC3038675)