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Nancy Woychik, PhD

Publications since 2011

Cruz, J. W. Sharp, J. D. Hoffer, E. D. Maehigashi, T. Vvedenskaya, I. O. Konkimalla, A. Husson, R. N. Nickels, B. E. Dunham, C. M. Woychik, N. A. Growth-regulating Mycobacterium tuberculosis VapC-mt4 toxin is an isoacceptor-specific tRNase. Nat Commun, 6:7480, . (PMID: 26158745)

Cruz, J. W. Woychik, N. A. Teaching Fido New ModiFICation Tricks. PLoS Pathog, 10:e1004349, . (PMID: 25255332, PMCID: PMC4177925)

Cruz, J. W. Rothenbacher, F. P. Maehigashi, T. Lane, W. S. Dunham, C. M. Woychik, N. A. Doc toxin is a kinase that inactivates elongation factor Tu. J Biol Chem, 289:7788-7798, . (PMID: 24448800, PMCID: PMC3953291)

Schifano, J. M. Woychik, N. A. 23S rRNA as an a-Maz-ing new bacterial toxin target. RNA Biol, 11:101-105, . (PMID: 24525465, PMCID: PMC3973728)

Schifano, J. M. Vvedenskaya, I. O. Knoblauch, J. G. Ouyang, M. Nickels, B. E. Woychik, N. A. An RNA-seq method for defining endoribonuclease cleavage specificity identifies dual rRNA substrates for toxin MazF-mt3. Nat Commun, 5:3538, . (PMID: 24709835, PMCID: PMC4090939)

Schifano, J. M. Edifor, R. Sharp, J. D. Ouyang, M. Konkimalla, A. Husson, R. N. Woychik, N. A. Mycobacterial toxin MazF-mt6 inhibits translation through cleavage of 23S rRNA at the ribosomal A site. Proc Natl Acad Sci U S A, 110:8501-8506, . (PMID: 23650345, PMCID: PMC3666664)

Rothenbacher, F. P. Suzuki, M. Hurley, J. M. Montville, T. J. Kirn, T. J. Ouyang, M. Woychik, N. A. Clostridium difficile MazF toxin exhibits selective, not global, mRNA cleavage. J Bacteriol, 194:3464-3474, . (PMID: 22544268, PMCID: PMC3434716)

Sharp, J. D. Cruz, J. W. Raman, S. Inouye, M. Husson, R. N. Woychik, N. A. Growth and translation inhibition through sequence-specific RNA binding by Mycobacterium tuberculosis VapC toxin. J Biol Chem, 287:12835-12847, . (PMID: 22354968, PMCID: PMC3339977)

Hurley, J. M. Cruz, J. W. Ouyang, M. Woychik, N. A. Bacterial Toxin RelE Mediates Frequent Codon-independent mRNA Cleavage from the 5' End of Coding Regions in Vivo. J Biol Chem, 286:14770-14778, . (PMID: 21324908, PMCID: PMC3083149)