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Nancy Woychik, PhD

Publications since 2011

Cruz, J. W. Rothenbacher, F. P. Maehigashi, T. Lane, W. S. Dunham, C. M. Woychik, N. A. Doc toxin is a kinase that inactivates elongation factor Tu. J Biol Chem, 289:7788-7798, . (PMID: 24448800, PMCID: PMC3953291)

Schifano, J. M. Woychik, N. A. 23S rRNA as an a-Maz-ing new bacterial toxin target. RNA Biol, 11:101-105, . (PMID: 24525465, PMCID: PMC3973728)

Schifano, J. M. Vvedenskaya, I. O. Knoblauch, J. G. Ouyang, M. Nickels, B. E. Woychik, N. A. An RNA-seq method for defining endoribonuclease cleavage specificity identifies dual rRNA substrates for toxin MazF-mt3. Nat Commun, 5:3538, . (PMID: 24709835, PMCID: PMC4090939)

Schifano, J. M. Edifor, R. Sharp, J. D. Ouyang, M. Konkimalla, A. Husson, R. N. Woychik, N. A. Mycobacterial toxin MazF-mt6 inhibits translation through cleavage of 23S rRNA at the ribosomal A site. Proc Natl Acad Sci U S A, 110:8501-8506, . (PMID: 23650345, PMCID: PMC3666664)

Rothenbacher, F. P. Suzuki, M. Hurley, J. M. Montville, T. J. Kirn, T. J. Ouyang, M. Woychik, N. A. Clostridium difficile MazF toxin exhibits selective, not global, mRNA cleavage. J Bacteriol, 194:3464-3474, . (PMID: 22544268, PMCID: PMC3434716)

Sharp, J. D. Cruz, J. W. Raman, S. Inouye, M. Husson, R. N. Woychik, N. A. Growth and translation inhibition through sequence-specific RNA binding by Mycobacterium tuberculosis VapC toxin. J Biol Chem, 287:12835-12847, . (PMID: 22354968, PMCID: PMC3339977)

Hurley, J. M. Cruz, J. W. Ouyang, M. Woychik, N. A. Bacterial Toxin RelE Mediates Frequent Codon-independent mRNA Cleavage from the 5' End of Coding Regions in Vivo. J Biol Chem, 286:14770-14778, . (PMID: 21324908, PMCID: PMC3083149)