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Ronald P. Hart, PhD

Publications since 2011

Grudzien-Nogalska, E. Jiao, X. Song, M. G. Hart, R. P. Kiledjian, M. Nudt3 is an mRNA decapping enzyme that modulates cell migration. RNA, In process, . (PMID: 26932476)

Carlson, A. L. Bennett, N. K. Francis, N. L. Halikere, A. Clarke, S. Moore, J. C. Hart, R. P. Paradiso, K. Wernig, M. Kohn, J. Pang, Z. P. Moghe, P. V. Generation and transplantation of reprogrammed human neurons in the brain using 3D microtopographic scaffolds. Nat Commun, 7:10862, . (PMID: 26983594)

De Filippis, L. Halikere, A. McGowan, H. Moore, J. C. Tischfield, J. A. Hart, R. P. Pang, Z. P. Ethanol-mediated activation of the NLRP3 inflammasome in iPS cells and iPS cells-derived neural progenitor cells. Mol Brain, 9:51, . (PMID: 27160314, PMCID: PMC4862119)

Lin, L. Swerdel, M. R. Lazaropoulos, M. P. Hoffman, G. S. Toro-Ramos, A. J. Wright, J. Lederman, H. Chen, J. Moore, J. C. Hart, R. P. Spontaneous ATM Gene Reversion in A-T iPSC to Produce an Isogenic Cell Line. Stem Cell Reports, 5:1097-1108, . (PMID: 26677768)

Jiang, D. Zhang, Y. Hart, R. P. Chen, J. Herrup, K. Li, J. Alteration in 5-hydroxymethylcytosine-mediated epigenetic regulation leads to Purkinje cell vulnerability in ATM deficiency. Brain, In process, . (PMID: 26510954)

Kraushar, M. L. Viljetic, B. Wijeratne, H. R. Thompson, K. Jiao, X. Pike, J. W. Medvedeva, V. Groszer, M. Kiledjian, M. Hart, R. P. Rasin, M. R. Thalamic WNT3 Secretion Spatiotemporally Regulates the Neocortical Ribosome Signature and mRNA Translation to Specify Neocortical Cell Subtypes. J Neurosci, 35:10911-10926, . (PMID: 26245956)

Siddiq, M. M. Hannila, S. S. Carmel, J. B. Bryson, J. B. Hou, J. Nikulina, E. Willis, M. R. Mellado, W. Richman, E. L. Hilaire, M. Hart, R. P. Filbin, M. T. Metallothionein-I/II promotes axonal regeneration in the Central Nervous System. J Biol Chem, In process, . (PMID: 25947372)

Guo, Y. Lee, J. H. Shu, L. Huang, Y. Li, W. Zhang, C. Yang, A. Y. Boyanapalli, S. S. Perekatt, A. Hart, R. P. Verzi, M. Kong, A. N. Association of aberrant DNA methylation in Apc(min/+) mice with the epithelial-mesenchymal transition and Wnt/beta-catenin pathways: genome-wide analysis using MeDIP-seq. Cell Biosci, 5:24, . (PMID: 26101583, PMCID: PMC4476183)

Carmel, J. B. Young, W. Hart, R. P. Flipping the transcriptional switch from myelin inhibition to axon growth in the CNS. Front Mol Neurosci, 8:34, . (PMID: 26236189, PMCID: PMC4505142)

Xie, P. Moore, C. R. Swerdel, M. R. Hart, R. P. Transcriptomic profiling of splenic B lymphomas spontaneously developed in B cell-specific TRAF3-deficient mice. Genom Data, 2:386-388, . (PMID: 25419513, PMCID: PMC4236829)

Yang, A. Y. Lee, J. H. Shu, L. Zhang, C. Su, Z. Y. Lu, Y. Huang, M. T. Ramirez, C. Pung, D. Huang, Y. Verzi, M. Hart, R. P. Kong, A. N. Genome-wide analysis of DNA methylation in UVB- and DMBA/TPA-induced mouse skin cancer models. Life Sci, 113:45-54, . (PMID: 25093921)

Kraushar, M. L. Thompson, K. Wijeratne, H. R. Viljetic, B. Sakers, K. Marson, J. W. Kontoyiannis, D. L. Buyske, S. Hart, R. P. Rasin, M. R. Temporally defined neocortical translation and polysome assembly are determined by the RNA-binding protein Hu antigen R. Proc Natl Acad Sci U S A, 111:E3815-E3824, . (PMID: 25157170)

Edwards, S. Baron, J. Moore, C. R. Liu, Y. Perlman, D. H. Hart, R. P. Xie, P. Mutated in colorectal cancer (MCC) is a novel oncogene in B lymphocytes. J Hematol Oncol, In process, . (PMID: 25200342, PMCID: PMC4172902)

Davila, J. L. Goff, L. A. Ricupero, C. L. Camarillo, C. Oni, E. N. Swerdel, M. R. Toro-Ramos, A. J. Li, J. Hart, R. P. A Positive Feedback Mechanism That Regulates Expression of miR-9 during Neurogenesis. PLoS One, 9:e94348, . (PMID: 24714615, PMCID: PMC3979806)

Li, J. Hart, R. P. Mallimo, E. M. Swerdel, M. R. Kusnecov, A. W. Herrup, K. EZH2-mediated H3K27 trimethylation mediates neurodegeneration in ataxia-telangiectasia. Nat Neurosci, 16:1745-1753, . (PMID: 24162653, PMCID: PMC3965909)

Deboer, E. M. Kraushar, M. L. Hart, R. P. Rasin, M. R. Post-transcriptional regulatory elements and spatiotemporal specification of neocortical stem cells and projection neurons. Neuroscience, In process, . (PMID: 23727006)

Hannila, S. S. Siddiq, M. M. Carmel, J. B. Hou, J. Chaudhry, N. Bradley, P. M. Hilaire, M. Richman, E. L. Hart, R. P. Filbin, M. T. Secretory leukocyte protease inhibitor reverses inhibition by CNS myelin, promotes regeneration in the optic nerve, and suppresses expression of the transforming growth factor-beta signaling protein Smad2. J Neurosci, 33:5138-5151, . (PMID: 23516280, PMCID: PMC3684282)

Komlos, D. Mann, K. D. Zhuo, Y. Ricupero, C. L. Hart, R. P. Liu, A. Y. Firestein, B. L. Glutamate dehydrogenase 1 and SIRT4 regulate glial development. Glia, 61:394-408, . (PMID: 23281078, PMCID: PMC3552040)

Ricupero, C. L. Swerdel, M. R. Hart, R. P. Epigenome analysis of pluripotent stem cells. Methods Mol Biol, 997:203-216, . (PMID: 23546758)

Sauvageau, M. Goff, L. A. Lodato, S. Bonev, B. Groff, A. F. Gerhardinger, C. Sanchez-Gomez, D. B. Hacisuleyman, E. Li, E. Spence, M. Liapis, S. C. Mallard, W. Morse, M. Swerdel, M. R. D'Ecclessis, M. F. Moore, J. C. Lai, V. Gong, G. Yancopoulos, G. D. Frendewey, D. Kellis, M. Hart, R. P. Valenzuela, D. M. Arlotta, P. Rinn, J. L. Multiple knockout mouse models reveal lincRNAs are required for life and brain development. Elife, 2:e01749, . (PMID: 24381249, PMCID: PMC3874104)

Mahishi, L. H. Hart, R. P. Lynch, D. R. Ratan, R. R. miR-886-3p Levels Are Elevated in Friedreich Ataxia. J Neurosci, 32:9369-9373, . (PMID: 22764244)

Li, H. Hader, A. T. Han, Y. R. Wong, J. A. Babiarz, J. Ricupero, C. L. Godfrey, S. B. Corradi, J. P. Fennell, M. Hart, R. P. Plummer, M. R. Grumet, M. Isolation of a novel rat neural progenitor clone that expresses Dlx family transcription factors and gives rise to functional GABAergic neurons in culture. Dev Neurobiol, 72:805-820, . (PMID: 21913335)

Li, J. Chen, J. Ricupero, C. L. Hart, R. P. Schwartz, M. S. Kusnecov, A. Herrup, K. Nuclear accumulation of HDAC4 in ATM deficiency promotes neurodegeneration in ataxia telangiectasia. Nat Med, 18:783-790, . (PMID: 22466704, PMCID: PMC3378917)

Pichardo-Casas, I. Goff, L. A. Swerdel, M. R. Athie, A. Davila, J. Ramos-Brossier, M. Lapid-Volosin, M. Friedman, W. J. Hart, R. P. Vaca, L. Expression profiling of synaptic microRNAs from the adult rat brain identifies regional differences and seizure-induced dynamic modulation. Brain Res, 1436:20-33, . (PMID: 22197703)

Ma, L. Yu, Y. M. Guo, Y. Hart, R. P. Schachner, M. Cysteine- and glycine-rich protein 1a is involved in spinal cord regeneration in adult zebrafish. Eur J Neurosci, 35:353-365, . (PMID: 22288476)

Yu, Y. M. Gibbs, K. M. Davila, J. Campbell, N. Sung, S. Todorova, T. I. Otsuka, S. Sabaawy, H. E. Hart, R. P. Schachner, M. MicroRNA miR-133b is essential for functional recovery after spinal cord injury in adult zebrafish. Eur J Neurosci, 33:1587-1597, . (PMID: 21447094, PMCID: PMC3100659)

Guo, Y. Ma, L. Cristofanilli, M. Hart, R. P. Hao, A. Schachner, M. Transcription factor Sox11b is involved in spinal cord regeneration in adult zebrafish. Neuroscience, 172:329-341, . (PMID: 20951776, PMCID: PMC3292217)

Camarillo, C. Swerdel, M. Hart, R. P. Comparison of microarray and quantitative real-time PCR methods for measuring MicroRNA levels in MSC cultures. Methods Mol Biol, 698:419-429, . (PMID: 21431535)