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Eduardo D. Sontag, PhD

Publications since 2011

Nikolaev, E. V. Sontag, E. D. Quorum-Sensing Synchronization of Synthetic Toggle Switches: A Design Based on Monotone Dynamical Systems Theory. PLoS Comput Biol, 12:e1004881, . (PMID: 27128344, PMCID: PMC4851387)

Raveh, A. Margaliot, M. Sontag, E. D. Tuller, T. A model for competition for ribosomes in the cell. J R Soc Interface, 13:, . (PMID: 26962028)

Ascensao, J. A. Datta, P. Hancioglu, B. Sontag, E. Gennaro, M. L. Igoshin, O. A. Non-monotonic Response to Monotonic Stimulus: Regulation of Glyoxylate Shunt Gene-Expression Dynamics in Mycobacterium tuberculosis. PLoS Comput Biol, 12:e1004741, . (PMID: 26900694)

Kang, T. Moore, R. Li, Y. Sontag, E. Bleris, L. Discriminating direct and indirect connectivities in biological networks. Proc Natl Acad Sci U S A, In process, . (PMID: 26420864)

Bastiaens, P. Birtwistle, M. R. Bluthgen, N. Bruggeman, F. J. Cho, K. H. Cosentino, C. de la Fuente, A. Hoek, J. B. Kiyatkin, A. Klamt, S. Kolch, W. Legewie, S. Mendes, P. Naka, T. Santra, T. Sontag, E. Westerhoff, H. V. Kholodenko, B. N. Silence on the relevant literature and errors in implementation. Nat Biotechnol, 33:336-339, . (PMID: 25850052)

Skataric, M. Nikolaev, E. V. Sontag, E. D. Fundamental limitation of the instantaneous approximation in fold-change detection models. IET Syst Biol, 9:1-15, . (PMID: 25569859)

Sontag, E. D. A technique for determining the signs of sensitivities of steady states in chemical reaction networks. IET Syst Biol, 8:251-267, . (PMID: 25478700)

Prabakaran, S. Gunawardena, J. Sontag, E. Paradoxical results in perturbation-based signaling network reconstruction. Biophys J, 106:2720-2728, . (PMID: 24940789, PMCID: PMC4070074)

Margaliot, M. Sontag, E. D. Tuller, T. Entrainment to periodic initiation and transition rates in a computational model for gene translation. PLoS One, 9:e96039, . (PMID: 24800863, PMCID: PMC4011696)

Segall-Shapiro, T. H. Meyer, A. J. Ellington, A. D. Sontag, E. D. Voigt, C. A. A 'resource allocator' for transcription based on a highly fragmented T7 RNA polymerase. Mol Syst Biol, 10:742, . (PMID: 25080493)

White, A. Lees, B. Kao, H. L. Cipriani, G. Paaby, A. Sontag, E. Erickson, K. Geiger, D. Gunsalus, K. Piano, F. DevStaR: High-throughput quantification of <i>C. elegans</i> developmental stages. IEEE Trans Med Imaging, 32:1791-1803, . (PMID: 23722463)

Kang, T. White, J. T. Xie, Z. Benenson, Y. Sontag, E. Bleris, L. Reverse engineering validation using a benchmark synthetic gene circuit in human cells. ACS Synth Biol, 2:255-262, . (PMID: 23654266, PMCID: PMC3716858)

Aminzare, Z. Sontag, E. D. Logarithmic Lipschitz norms and diffusion-induced instability. Nonlinear Anal Theory Methods Appl, 83:31-49, . (PMID: 23729972, PMCID: PMC3666191)

Barton, J. P. Sontag, E. D. The energy costs of insulators in biochemical networks. Biophys J, 104:1380-1390, . (PMID: 23528097, PMCID: PMC3602777)

Hamadeh, A. Ingalls, B. Sontag, E. Transient dynamic phenotypes as criteria for model discrimination: fold-change detection in Rhodobacter sphaeroides chemotaxis. J R Soc Interface, 10:20120935, . (PMID: 23293140, PMCID: PMC3565743)

Liu, L. Duclos, G. Sun, B. Lee, J. Wu, A. Kam, Y. Sontag, E. D. Stone, H. A. Sturm, J. C. Gatenby, R. A. Austin, R. H. Minimization of thermodynamic costs in cancer cell invasion. Proc Natl Acad Sci U S A, 110:1686-1691, . (PMID: 23319630, PMCID: PMC3562811)

Shimoga, V. White, J. T. Li, Y. Sontag, E. Bleris, L. Synthetic mammalian transgene negative autoregulation. Mol Syst Biol, 9:670, . (PMID: 23736683)

Wood, K. Nishida, S. Sontag, E. D. Cluzel, P. Mechanism-independent method for predicting response to multidrug combinations in bacteria. Proc Natl Acad Sci U S A, 109:12254-12259, . (PMID: 22773816, PMCID: PMC3409729)

Miller, M. Hafner, M. Sontag, E. Davidsohn, N. Subramanian, S. Purnick, P. E. Lauffenburger, D. Weiss, R. Modular Design of Artificial Tissue Homeostasis: Robust Control through Synthetic Cellular Heterogeneity. PLoS Comput Biol, 8:e1002579, . (PMID: 22829755, PMCID: PMC3400602)

Skataric, M. Sontag, E. D. A characterization of scale invariant responses in enzymatic networks. PLoS Comput Biol, 8:e1002748, . (PMID: 23133355, PMCID: PMC3486845)

Albert, R. DasGupta, B. Hegde, R. Sivanathan, G. S. Gitter, A. Gursoy, G. Paul, P. Sontag, E. Computationally efficient measure of topological redundancy of biological and social networks. Phys Rev E Stat Nonlin Soft Matter Phys, 84:036117, . (PMID: 22060466)

Jiang, P. Ventura, A. C. Sontag, E. D. Merajver, S. D. Ninfa, A. J. Del Vecchio, D. Load-induced modulation of signal transduction networks. Sci Signal, 4:ra67, . (PMID: 21990429)

Bleris, L. Xie, Z. Glass, D. Adadey, A. Sontag, E. Benenson, Y. Synthetic incoherent feedforward circuits show adaptation to the amount of their genetic template. Mol Syst Biol, 7:519, . (PMID: 21811230, PMCID: PMC3202791)