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Sharon R. Pine, PhD

Selected Publications

  1. Wiemels JL, Leonard BC, Wang Y, Segal MR, Hunger SP, Smith MT, Crouse V, Ma X, Buffler PA, and Pine SR: Site-specific translocation and evidence of postnatal origin of the t(1;19) E2A-PBX1 fusion in childhood acute lymphoblastic leukemia. Proc Natl Acad Sci USA 99:15101-15106, 2002. PMCID: PMC137550.
  2. Pine SR, Gill RK, Levendoglu-Tugal O, Ozkaynak MF, Sandoval C, and Jayabose S: Real-time Quantitative PCR -Standardized detection of minimal residual disease in pediatric acute lymphoblastic leukemia. J Ped Hematol Oncol 25: 103-108, 2003. PMID: 12571459
  3. Pine SR, Guo X, Yin C, Jayabose S, Levendoglu-Tugal O, Ozkaynak MF, and Sandoval C: GATA1 as a new target to detect minimal residual disease in both transient leukemia and megakaryoblastic leukemia of Down syndrome. Leuk Res 29: 1353-1356, 2005. PMID: 15916804
  4. Pine SR, Mechanic LV, Bowman ED, Welsh JA, Chanock SC, Shields PG, and Harris CC: MDM2 SNP309 and SNP354 are not associated with lung cancer risk. Cancer Epidemiol Biomarkers Prev 15: 1559-1561, 2006. PMID: 16896050
  5. Pine SR, Jayabose S, Yin CH, Drushel C, and Sandoval C: Incidence and clinical implications of GATA1 mutations in newborns with Down Syndrome. Blood 110: 2128-2131, 2007. PMID: 17576817
  6. Pine SR, Mechanic LE, Ambs S, Bowman ED, Chanock SJ, Loffredo C, Shields PG, and Harris CC: Lung cancer survival and functional polymorphisms in MBL2, an innate immunity gene. J Natl Cancer Inst 99: 1401-1409, 2007. PMID: 17848669
  7. Pine SR, Marshall B, and Varticovski L: Lung cancer stem cells. Dis Markers 24: 257-66, 2008.  PMCID: PMC3850541.
  8. Fujita K, Mondal AM, Horikawa I, Nguyen GH, Kumamoto K, Sohn JJ, Bowman ED, Mathe EA, Schetter AJ, Pine SR, Ji H, Vojtesek B, Bourdon JC, Lane DP, and Harris CC. p53 isoforms Delta-133p53 and p53beta are endogenous regulators of replicative cellular senescence. Nat Cell Biol 11, 1135-1142, 2009. PMCID: PMC2802853.
  9. Pine SR, Ryan BM, Varticovski L, Robles AI, and Harris CC: Microenvironmental modulation of asymmetric cell division in human lung cancer cells. Proc Nat Acad Sci USA 107, 2195-2000, 2010. PMCID: PMC2836660.
  10. Pine SR, Mechanic LE, Enewold L, Chaturvedi AK, Katki HA, Zheng YL, Bowman ED, Engels EA, Caporaso NE, and Harris CC: Increased levels of circulating interleukin 6, interleukin 8, C-reactive protein, and risk of lung cancer. J Natl Cancer Inst, 103, 1112-1122, 2011. PMCID: PMC3139587.
  11. Patel SA, Ramkissoon SH, Bryan M, Pliner LF, Dontu G, Patel PS, Amiri S, Pine SR, and Ramashwar P: Delineation of breast cancer cell hierarchy identifies the subset responsible for dormancy. Sci Reports, 2, 906, Epub, Nov 30, 2012. PMCID:  PMC3510468.
  12. Mondal AM, Horikawa I, Pine SR, Fujita K, Morgan KM, Vera E, Mazur SJ, Appella E, Vojtesek B, Blasco MA, Lane DP, and Harris CC: p53 isoforms regulate aging- and tumor-associated replicative senescence in T lymphocytes. J Clin Invest, 123, 5247-5257, 2013. PMCID: PMC24231352.
  13. Capaccione KM, and Pine SR: The Notch signaling pathway as a mediator of tumor survival. Carcinogenesis, 34, 1420-1430, 2013.  PMCID: PMC3697894.
  14. Liu W, Jeganathan G, Amiri S, Morgan KM, Ryan BM, and Pine SR: Asymmetric segregation of template DNA strands in basal-like human breast cancer cell lines. Mol Cancer, 12, Epub Nov 15, 2013. PMCID: PMC24238140.
  15. Capaccione KM, Hong X, Morgan KM, Liu W, Bishop JM, Liu LX, Markert E, Deen M, Minerowicz C, Bertino JR, Allen T, and Pine SR: Sox9 mediates Notch1-induced mesenchymal features in lung adenocarcinoma. Oncotarget, 2014