Researcher Profiles

Return to member profile

Derek B. Sant'Angelo, PhD

Publications since 2011

Chen, L. Foreman, D. P. Sant'Angelo, D. B. Krangel, M. S. Yin Yang 1 Promotes Thymocyte Survival by Downregulating p53. J Immunol, In process, . (PMID: 26843327)

Zhang, S. Laouar, A. Denzin, L. K. Sant'Angelo, D. B. Zbtb16 (PLZF) is stably suppressed and not inducible in non-innate T cells via T cell receptor-mediated signaling. Sci Rep, 5:12113, . (PMID: 26178856)

Lynch, L. Michelet, X. Zhang, S. Brennan, P. J. Moseman, A. Lester, C. Besra, G. Vomhof-Dekrey, E. E. Tighe, M. Koay, H. F. Godfrey, D. I. Leadbetter, E. A. Sant'Angelo, D. B. von Andrian, U. Brenner, M. B. Regulatory iNKT cells lack expression of the transcription factor PLZF and control the homeostasis of T cells and macrophages in adipose tissue. Nat Immunol, In process, . (PMID: 25436972)

Ghosh, A. Holland, A. M. Dogan, Y. Yim, N. L. Rao, U. K. Young, L. F. West, M. L. Singer, N. V. Lee, H. Na, I. K. Tsai, J. J. Jenq, R. R. Penack, O. Hanash, A. M. Lezcano, C. Murphy, G. F. Liu, C. Sadelain, M. Sauer, M. G. Sant'angelo, D. van den Brink, M. R. PLZF confers effector functions to donor T cells that preserve graft-versus-tumor effects while attenuating GVHD. Cancer Res, 73:4687-4696, . (PMID: 23733752, PMCID: PMC3732814)

Zhu, L. Qiao, Y. Choi, E. S. Das, J. Sant'angelo, D. B. Chang, C. H. A transgenic TCR directs the development of IL-4+ and PLZF+ innate CD4 T cells. J Immunol, 191:737-744, . (PMID: 23776174, PMCID: PMC3702648)

Monzon-Casanova, E. Paletta, D. Starick, L. Muller, I. Sant'angelo, D. B. Pyz, E. Herrmann, T. Direct identification of rat iNKT cells reveals remarkable similarities to human iNKT cells and a profound deficiency in LEW rats. Eur J Immunol, 43:404-415, . (PMID: 23165932)

Thapa, P. Das, J. McWilliams, D. Shapiro, M. Sundsbak, R. Nelson-Holte, M. Tangen, S. Anderson, J. Desiderio, S. Hiebert, S. Sant'angelo, D. B. Shapiro, V. S. The transcriptional repressor NKAP is required for the development of iNKT cells. Nat Commun, 4:1582, . (PMID: 23481390, PMCID: PMC3615467)

Osada, M. Singh, V. J. Wu, K. Sant'Angelo, D. B. Pezzano, M. Label retention identifies a multipotent mesenchymal stem cell-like population in the postnatal thymus. PLoS One, 8:e83024, . (PMID: 24340075, PMCID: PMC3858364)

Qiao, Y. Zhu, L. Sofi, H. Lapinski, P. E. Horai, R. Mueller, K. Stritesky, G. L. He, X. Teh, H. S. Wiest, D. L. Kappes, D. J. King, P. D. Hogquist, K. A. Schwartzberg, P. L. Sant'angelo, D. B. Chang, C. H. Development of promyelocytic leukemia zinc finger-expressing innate CD4 T cells requires stronger T-cell receptor signals than conventional CD4 T cells. Proc Natl Acad Sci U S A, 109:16264-16269, . (PMID: 22988097, PMCID: PMC3479572)

Beaulieu, A. M. Sant'Angelo, D. B. The BTB-ZF family of transcription factors: key regulators of lineage commitment and effector function development in the immune system. J Immunol, 187:2841-2847, . (PMID: 21900183, PMCID: PMC3170133)

Amrani, Y. M. Gill, J. Matevossian, A. Alonzo, E. S. Yang, C. Shieh, J. H. Moore, M. A. Park, C. Y. Sant'Angelo, D. B. Denzin, L. K. The Paf oncogene is essential for hematopoietic stem cell function and development. J Exp Med, 208:1757-1765, . (PMID: 21844206, PMCID: PMC3171089)

Gordon, S. M. Carty, S. A. Kim, J. S. Zou, T. Smith-Garvin, J. Alonzo, E. S. Haimm, E. Sant'Angelo, D. B. Koretzky, G. A. Reiner, S. L. Jordan, M. S. Requirements for eomesodermin and promyelocytic leukemia zinc finger in the development of innate-like CD8+ T cells. J Immunol, 186:4573-4578, . (PMID: 21383242, PMCID: PMC3085897)

Alonzo, E. S. Sant'Angelo, D. B. Development of PLZF-expressing innate T cells. Curr Opin Immunol, 23:220-227, . (PMID: 21257299, PMCID: PMC3073746)

Eidson, M. Wahlstrom, J. Beaulieu, A. M. Zaidi, B. Carsons, S. E. Crow, P. K. Yuan, J. Wolchok, J. D. Horsthemke, B. Wieczorek, D. Sant'Angelo, D. B. Altered development of NKT cells, gammadelta T cells, CD8 T cells and NK cells in a PLZF deficient patient. PLoS One, 6:e24441, . (PMID: 21915328, PMCID: PMC3167854)

Li, J. Vandal, O. Sant'Angelo, D. B. TCR affinity for self-ligands influences the development and function of encephalitogenic T cells. PLoS One, 6:e17702, . (PMID: 21437282, PMCID: PMC3060088)