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XiangLin Tan, MD, PhD

Publications since 2011

Jansen, R. J. Tan, X. L. Petersen, G. M. Gene-by-Environment Interactions in Pancreatic Cancer: Implications for Prevention. Yale J Biol Med, 88:115-126, . (PMID: 26029010, PMCID: PMC4445433)

Yue, W. Zheng, X. Lin, Y. Yang, C. S. Xu, Q. Carpizo, D. Huang, H. DiPaola, R. S. Tan, X. L. Metformin combined with aspirin significantly inhibit pancreatic cancer cell growth in vitro and in vivo by suppressing anti-apoptotic proteins Mcl-1 and Bcl-2. Oncotarget, In process, . (PMID: 26056043)

Tan, X. L. Bhattacharyya, K. K. Dutta, S. K. Bamlet, W. R. Rabe, K. G. Wang, E. Smyrk, T. C. Oberg, A. L. Petersen, G. M. Mukhopadhyay, D. Metformin Suppresses Pancreatic Tumor Growth With Inhibition of NFkappaB/STAT3 Inflammatory Signaling. Pancreas, 44:636-647, . (PMID: 25875801, PMCID: PMC4399019)

Yue, W. Wang, T. Zachariah, E. Lin, Y. Yang, C. S. Xu, Q. DiPaola, R. S. Tan, X. L. Transcriptomic analysis of pancreatic cancer cells in response to metformin and aspirin: an implication of synergy. Sci Rep, 5:13390, . (PMID: 26294325)

Yue, W. Yang, C. S. Dipaola, R. S. Tan, X. L. Repurposing of metformin and aspirin by targeting AMPK-mTOR and inflammation for pancreatic cancer prevention and treatment. Cancer Prev Res (Phila), 7:388-397, . (PMID: 24520038)

Fridley, B. L. Abo, R. Tan, X. L. Jenkins, G. D. Batzler, A. Moyer, A. M. Biernacka, J. M. Wang, L. Integrative Gene Set Analysis: Application to Platinum Pharmacogenomics. OMICS, 18:34-41, . (PMID: 24199607, PMCID: PMC3903166)

Jansen, R. J. Robinson, D. P. Stolzenberg-Solomon, R. Z. Bamlet, W. R. Tan, X. Cunningham, J. M. Li, Y. Rider, D. N. Oberg, A. L. Rabe, K. G. Anderson, K. E. Sinha, R. Petersen, G. M. Polymorphisms in metabolism/antioxidant genes may mediate the effect of dietary intake on pancreatic cancer risk. Pancreas, 42:1043-1053, . (PMID: 24051964, PMCID: PMC3779344)

Tan, X. L. Marquardt, G. Massimi, A. B. Shi, M. Han, W. Spivack, S. D. High-throughput library screening identifies two novel NQO1 inducers in human lung cells. Am J Respir Cell Mol Biol, 46:365-371, . (PMID: 22021338, PMCID: PMC3326428)

Tan, X. L. Reid Lombardo, K. M. Bamlet, W. R. Oberg, A. L. Robinson, D. P. Anderson, K. E. Petersen, G. M. Aspirin, nonsteroidal anti-inflammatory drugs, acetaminophen, and pancreatic cancer risk: a clinic-based case-control study. Cancer Prev Res (Phila), 4:1835-1841, . (PMID: 21803981, PMCID: PMC3208748)

Tan, X. L. Moyer, A. M. Fridley, B. L. Schaid, D. J. Niu, N. Batzler, A. J. Jenkins, G. D. Abo, R. P. Li, L. Cunningham, J. M. Sun, Z. Yang, P. Wang, L. Genetic variation predicting cisplatin cytotoxicity associated with overall survival in lung cancer patients receiving platinum-based chemotherapy. Clin Cancer Res, 17:5801-5811, . (PMID: 21775533, PMCID: PMC3167019)