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Peter Lobel, PhD

Publications since 2011

Meng, Y. Sohar, I. Sleat, D. E. Richardson, J. R. Reuhl, K. R. Jenkins, R. B. Sarkar, G. Lobel, P. Effective Intravenous Therapy for Neurodegenerative Disease With a Therapeutic Enzyme and a Peptide That Mediates Delivery to the Brain. Mol Ther, 22:547-553, . (PMID: 24394185, PMCID: PMC3944336)

Huang, L. Pike, D. Sleat, D. E. Nanda, V. Lobel, P. Potential pitfalls and solutions for use of fluorescent fusion proteins to study the lysosome. PLoS One, 9:e88893, . (PMID: 24586430, PMCID: PMC3931630)

Sleat, D. E. Sun, P. Wiseman, J. A. Huang, L. El-Banna, M. Zheng, H. Moore, D. F. Lobel, P. Extending the mannose 6-phosphate glycoproteome by high resolution/accuracy mass spectrometry analysis of control and acid phosphatase 5-deficient mice. Mol Cell Proteomics, 12:1806-1817, . (PMID: 23478313, PMCID: PMC3708167)

Sleat, D. E. Wiseman, J. A. Sohar, I. El-Banna, M. Zheng, H. Moore, D. F. Lobel, P. Proteomic analysis of mouse models of Niemann-Pick C disease reveals alterations in the steady-state levels of lysosomal proteins within the brain. Proteomics, 12:3499-3509, . (PMID: 23070805, PMCID: PMC3651901)

Meng, Y. Sohar, I. Wang, L. Sleat, D. E. Lobel, P. Systemic administration of tripeptidyl peptidase I in a mouse model of late infantile neuronal ceroid lipofuscinosis: effect of glycan modification. PLoS One, 7:e40509, . (PMID: 22792360, PMCID: PMC3391252)

Vuillemenot, B. R. Katz, M. L. Coates, J. R. Kennedy, D. Tiger, P. Kanazono, S. Lobel, P. Sohar, I. Xu, S. Cahayag, R. Keve, S. Koren, E. Bunting, S. Tsuruda, L. S. O'Neill, C. A. Intrathecal tripeptidyl-peptidase 1 reduces lysosomal storage in a canine model of late infantile neuronal ceroid lipofuscinosis. Mol Genet Metab, 104:325-337, . (PMID: 21784683)

Xu, S. Wang, L. El-Banna, M. Sohar, I. Sleat, D. E. Lobel, P. Large-volume intrathecal enzyme delivery increases survival of a mouse model of late infantile neuronal ceroid lipofuscinosis. Mol Ther, 19:1842-1848, . (PMID: 21730969, PMCID: PMC3188738)

Della Valle, M. C. Sleat, D. E. Zheng, H. Moore, D. F. Jadot, M. Lobel, P. Classification of Subcellular Location by Comparative Proteomic Analysis of Native and Density-shifted Lysosomes. Mol Cell Proteomics, 10:M110.006403, . (PMID: 21252268, PMCID: PMC3069348)

Dixit, S. S. Jadot, M. Sohar, I. Sleat, D. E. Stock, A. M. Lobel, P. Loss of Niemann-Pick C1 or C2 protein results in similar biochemical changes suggesting that these proteins function in a common lysosomal pathway. PLoS One, 6:e23677, . (PMID: 21887293, PMCID: PMC3161064)