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A Phase 1b Multicenter, Open-label, Study of JNJ-90009530, an Autologous Anti-CD20 CAR-T Cell Therapy in Adult Participants with Relapsed or Refractory B-cell Non- Hodgkin Lymphoma

The primary objectives are to assess the safety and tolerability of JNJ-90009530 and to determine the
recommended Phase 2 dose(s)(RP2D[s]). Secondary objectives are to evaluate the preliminary efficacy of
JNJ-90009530 in participants with r/r B-NHL and to characterize JNJ-90009530 pharmacokinetics (PK) in blood.

Protocol Number: 012317
Phase: Phase I
Applicable Disease Sites: Non-Hodgkin's Lymphoma
Drugs Involved: JNJ-90009530
Principal Investigator: Matthew Matasar
Scope: National
Therapies Involved: Chemotherapy single agent systemic
Participating Institutions:
  • Rutgers University
Inclusion & Exclusion Criteria

Please note that we have obtained the inclusion and exclusion criteria information from the National Institutes of Health’s clinical trials web site ClinicalTrials.gov. The listed criteria may not necessarily reflect recent amendments to the protocol and the current criteria.

For further information about clinical trials, please contact us at 732-235-7356.