Wang Laboratory – Select Publications

  1. Wang Y, Lu H, Czap MS, Beg M, Kim H, Liu J, Wang H, Masaka P, Romanienko P, Shen Z. The methylation of KU70 coordinates cell fate determination in DNA damage repair and tumorigenesis. In preparation.

  2. Wang Y#, Czap MS, Kim H, Masaka PM, Wang H, Beg MA, Lu H, Liu J, Chang Y, Romanienko P, Montagna C, Shen Z#. The mammalian KU70 C-terminus SAP domain is required to repair DNA damage. Nucleic Acid Research, 2025, June 24; 53 (11). doi: 10.1093/nar/gkaf499. (BioRxiv. DOI: https://doi.org/10.1101/2024.06.30.601420) (#co-corresponding author)

  3. Han F, Simeroth S, Zhu J, Gryniuk I, Pranay A, Chen W, Wang Y, Cai Y, Shen Z, Wang G, Griffin C, Xia L, Yu P. Lymphatic endothelial mTORC1 instructs metabolic and developmental signaling during lymphangiogenesis. Developmental Cell. 2025, May 7; online. doi: 10.1016/j.devcel.2025.04.012. 

  4. Lu H*, Wang Y*, Chaudhary S, Balaga V, Ke H, Shi F, Liu J, Huo Y, Romanienko P, Xia B, De S, Chan SC, Shen Z. Medulloblastomas initiated by homologous recombination defects in mice. The American Journal of Pathology, 2024, Aug 19: S0002-9440(24)00294-3. (PubMed PMID: 39168365; DOI: 10.1016/j.ajpath.2024.07.018 (*co-first author).

  5. Jaiswal RK, Lei KH, Chastain M, Wang Y, Shiva O, Li S, You Z, Chi P, Chai W. CaMKK2 and CHK1 phosphorylate human STN1 in response to replication stress to protect stalled forks from aberrant resection. Nature communication. 2023, Nov 30; 14(1): 7882. PubMed PMID: 38036565; PMCID: PMC10689503; doi: 10.1038/s41467-023-43685-2

  6. Wang Y, Liu B, Lu H, Liu J, Romanienko P, Montelione GT, Shen Z. SETD4 mediated KU70 methylation suppresses apoptosis. Cell Reports, 2022, 39, 110794. doi: 10.1016/j.celrep.2022.110794. PubMed PMID: 35545041; PubMed Central PMCID: PMC9201767.

  7. Wang Y, Shen Z. Unmasking the mammalian SET domain-containing protein 4. NAR Cancer, 2022, 4(3). doi: 10.1093/narcan/zcac021. PubMed PMID: 35854936; PubMed Central PMCID: PMC9277757.

  8. Chai W, Chastain M, Shiva O, Wang Y. The intrinsically disordered region in the human STN1 OB-fold domain is important for protecting genome stability. Biology (Basel). 2021 Sep 28; 10(10):977. doi: 10.3390/biology10100977. PubMed PMID: 34681076; PubMed Central PMCID: PMC8533325.

  9. Wang Y, Chai W. Pathogenic CTC1 mutations cause global genome instabilities under replication stress. Nucleic Acid Research. 2018, 46(8): 3981-3992. doi: 10.1093/nar/gky114. PubMed PMID: 29481669; PubMed Central PMCID: PMC5934659. 

  10. Wang Y, Yuan L, Yang X, Wei D, Wang B, Sun X, Feng F, Nan G, Chen Z, Bian H. A Chimeric Antibody Targeting CD147 Inhibits Hepatocellular Carcinoma Cell Motility via FAK-PI3K-Akt-Girdin Signaling Pathway. Clinical & Experimental Metastasis. 2015, 32(1): 39-53. doi: 10.1007/s10585-014-9689-7. Epub 2014 Nov 26. PubMed PMID: 25424030. 

  11. Wei D, Li Q, Wang X, Wang Y, Xu J, Feng F, Nan G, Wang B, Li C, Guo T, Chen Z, Bian H. Oncolytic Newcastle disease virus expressing chimeric antibody enhanced anti-tumor efficacy in orthotopic hepatoma-bearing mice. J Exp Clin Cancer Res. 2015, 34: 153. doi: 10.1186/s13046-015-0271-1. PubMed PMID: 26689432; PubMed Central PMCID: PMC4687166. 

  12. Wang Y, Su XM, Liu J, Zhang T, Wang XB, Liu QH. The sonodynamic effect of HMME on the proliferation of U937 cells. Journal of Shaanxi Normal University (Natural Science Edition). 2014, 42(2).

  13. Wei D, Sun N, Nan G, Wang Y, Liu H, Peeters B, Chen Z, Bian H. Construction of recombinant Newcastle disease virus Italien strain for oncolytic virotherapy of tumors. Hum Gene Ther. 2012, 23(7): 700-10. doi: 10.1089/hum.2011.207. Epub 2012 Apr 18. PubMed PMID: 22372930.