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Radiation
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A Phase 1/2 Trial of Selinexor (KPT-330) and Radiation Therapy in Newly-Diagnosed Pediatric Diffuse Intrinsic Pontine Glioma (DIPG) and High-Grade Glioma (HGG).
Protocol: 112203Principal Investigator:
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Scott A Moerdler
Applicable Disease Sites: Brain and Nervous System -
A Prospective Phase 3 Study of Patients with Newly Diagnosed Very Low-risk and Low-risk Fusion Negative Rhabdomyosarcoma.
Protocol: 112205Principal Investigator:
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Scott A Moerdler
Applicable Disease Sites: Soft Tissue -
A Phase 2 Study of Dabrafenib with Trametinib after Local Irradiation in Newly-Diagnosed BRAFV600-Mutant High-Grade Glioma (HGG).
Protocol: 112302Applicable Disease Sites: Brain and Nervous System
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A Randomized Phase 3 Interim Response Adapted Trial Comparing Standard Therapy with Immuno-Oncology Therapy for Children and Adults with Newly Diagnosed Stage I and II Classic Hodgkin Lymphoma
Protocol: 112305Principal Investigator:
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Richard A Drachtman
Applicable Disease Sites: Hodgkin's Lymphoma -
A Phase 3 Randomized, Placebo-Controlled Trial Evaluating Memantine for Neurocognitive Protection in Children Undergoing Cranial Radiotherapy as Part of Treatment for Primary Central Nervous System Tumors.
Protocol: 112306Principal Investigator:
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Peter D. Cole
Applicable Disease Sites: Brain and Nervous System -
A Phase 2 Study of SNDX-5613 in Combination with Chemotherapy for Patients with Relapsed or Refractory KMT2A-Rearranged Infant Leukemia.
Protocol: 112402Principal Investigator:
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Richard A Drachtman
Applicable Disease Sites: Leukemia, other -
ARAR2221: A Phase 2 Study Using Chemoimmunotherapy with Gemcitabine, Cisplatin and Nivolumab in Newly Diagnosed Nasopharyngeal Carcinoma (NPC)
Protocol: 112405Principal Investigator:
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Scott A Moerdler
Applicable Disease Sites: Lip, Oral Cavity and Pharynx -
Web-Based Coping and Communication Skills Intervention for Women who are newly diagnosed with Gynecological Cancer: A Pilot Study.
Protocol: 131908Principal Investigator:
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Sharon Manne
Applicable Disease Sites: Cervix
Ovary -
Bright IDEAS-Young Adults: Problem-Solving Skills Training to Reduce Distress Among Young Adults with Cancer.
Protocol: 131911Principal Investigator:
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Katie Devine
Applicable Disease Sites: Any Site -
Phase III Trial of Lomustine-Temozolomide Combination Therapy Versus Standard Temozolomide in Patients with Methylated MGMT Promoter Glioblastoma.
Protocol: 142202Applicable Disease Sites: Brain and Nervous System
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NRG-BN012, A Randomized Phase III Trial of Pre-Operative Compared to Post-Operative Stereotactic Radiosurgery in Patients with Resectable Brain Metastases
Protocol: 142302Principal Investigator:
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Nicholas DeNunzio
Applicable Disease Sites: Brain and Nervous System -
Phase III Trial of Single Fraction Stereotactic Radiosurgery (SRS) Versus Fractionated SRS (FSRS) for Intact Brain Metastases.
Protocol: 142403Applicable Disease Sites: Brain and Nervous System
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Cardiotoxicity in Locally Advanced Lung Cancer Patients Treated with Chemoradiation Therapy: A Prospective Longitudinal Cohort.
Protocol: 152101Principal Investigator:
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Salma Jabbour
Applicable Disease Sites: Lung -
Palliative Dose Escalated Radiation for Painful Non-Spine Bone Metastases and Painful Non-Bone Metastases: A Phase II Study.
Protocol: 152201Principal Investigator:
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Matthew Deek
Applicable Disease Sites: Any Site -
The Radiation Oncology-Biology Integration Network (ROBIN) Molecular Characterization Trial (MCT) of Standard Short Course Radiotherapy for Rectal Cancer.
Protocol: 152301Principal Investigator:
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Salma Jabbour
Applicable Disease Sites: Rectum -
Phase 2 Study of Paclitaxel + Ipatasertib in Taxane-Refractory Participants with AKT-Altered Advanced Non-Breast Solid Tumors.
Protocol: 172404Principal Investigator:
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Eugenia Girda
Applicable Disease Sites: Any Site