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A Phase IA/IB, Open Label, Multicenter, Dose-Escalation Study to Evaluate the Safety, Pharmacokinetics, and Activity of RO7502175 as a Single Agent and in Combination with Atezolizumab in Patients with Locally Advanced or Metastatic Solid Tumors.

This study will evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, immunogenicity, and preliminary anti-tumor activity of RO7502175 as a single agent (Phase Ia) or in combination with the anti-PD-L1 antibody, atezolizumab (Phase Ib), in patients with locally advanced or metastatic solid tumors. Specific objectives and corresponding endpoints for the study.

Protocol Number: 052212
Phase: Phase I
Applicable Disease Sites: Any Site
Drugs Involved: Atezolizumab (MPDL3280A)
RO7502175
Principal Investigator: Sanjay Goel
Scope: Local
Therapies Involved: Chemotherapy multiple agents systemic
Participating Institutions:
  • Rutgers University
Inclusion & Exclusion Criteria

Please note that we have obtained the inclusion and exclusion criteria information from the National Institutes of Health’s clinical trials web site ClinicalTrials.gov. The listed criteria may not necessarily reflect recent amendments to the protocol and the current criteria.

For further information about clinical trials, please contact us at 732-235-7356.