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A Prospective Registry of Spine Cancer Patients Undergoing Surgical decompression followed by Radiation Therapy for Spine Tumors
Protocol: 002575Principal Investigator:
- Jonathan Sherman
Applicable Disease Sites: Brain and Nervous System -
PDX model in zebrafish to understand the role of BBB modulation on tumor treatments
Protocol: 002581Principal Investigator:
- Jonathan Sherman
Applicable Disease Sites: Brain and Nervous System -
Remote Bimanual Virtual Rehabilitation for Elderly with Cerebral Vascular Disease
Protocol: 042014Principal Investigator:
- Jasdeep S Hundal
Applicable Disease Sites: Brain and Nervous System -
A Phase 1/2 Trial of Selinexor (KPT-330) and Radiation Therapy in Newly-Diagnosed Pediatric Diffuse Intrinsic Pontine Glioma (DIPG) and High-Grade Glioma (HGG).
Protocol: 112203Principal Investigator:
- Nehal Parikh
Applicable Disease Sites: Brain and Nervous System -
A Phase 3 Study of Dinutuximab Added to Intensive Multimodal Therapy for Children with Newly Diagnosed High-Risk Neuroblastoma.
Protocol: 112404Principal Investigator:
- Nehal Parikh
Applicable Disease Sites: Brain and Nervous System -
A Phase II Trial Evaluating Chemotherapy followed by Response-Based Reduced Radiation Therapy for Patients with Central Nervous System Germinomas.
Protocol: 112409Principal Investigator:
- Nehal Parikh
Applicable Disease Sites: Brain and Nervous System -
Collection of Pediatric and Adult Research Specimens for CNS Malignancies.
Protocol: 112503Principal Investigator:
- Nehal Parikh
Applicable Disease Sites: Brain and Nervous System -
A Phase 3 Study of Sodium Thiosulfate for the Reduction of Cisplatin-Induced Ototoxicity in Children with Average-Risk Medulloblastoma and Reduced Therapy for Children with Medulloblastoma with Low-Risk Features.
Protocol: 112509Principal Investigator:
- Nehal Parikh
Applicable Disease Sites: Brain and Nervous System -
A Phase 1 and Randomized Phase 2 Trial of Selinexor and Temozolomide in Recurrent Glioblastoma.
Protocol: 142301Applicable Disease Sites: Brain and Nervous System
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Randomized Study of DOC1021 Dendritic Cell Immunotherapy in Combination with Standard of Care for Newly Diagnosed Adult Glioblastoma
Protocol: 142501Principal Investigator:
- Morana Vojnic
Applicable Disease Sites: Brain and Nervous System -
A Phase 2, Multicenter, Clinical Study to Evaluate the Efficacy and Safety of Safusidenib Erbumine in Patients with Isocitrate Dehydrogenase 1 (IDH1)-Mutant Glioma.
Protocol: 142502Principal Investigator:
- Morana Vojnic
Applicable Disease Sites: Brain and Nervous System -
A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of Optune® (TTFields, 200 kHz) Concomitant with Maintenance Temozolomide and Pembrolizumab Versus Optune® Concomitant with Maintenance Temozolomide and Placebo for the Treatment of Newly Diagnosed Glioblastoma (EF-41/KEYNOTE D58)
Protocol: 142504Principal Investigator:
- Morana Vojnic
Applicable Disease Sites: Brain and Nervous System -
A Phase 2 Randomized, Multicenter Study to Evaluate the Efficacy and Safety of Silevertinib, an Oral EGFR Inhibitor, in Combination with Temozolomide in Patients with Newly Diagnosed Glioblastoma with Unmethylated MGMT Promoter and EGFRvIII.
Protocol: 142602Principal Investigator:
- Morana Vojnic
Applicable Disease Sites: Brain and Nervous System