Social Genomic Mechanisms of Health Disparities among Adolescent and Young Adult (AYA) Survivors of Hodgkin and Non-Hodgkin Lymphoma.
Primary Objectives:
1. To establish the association of social-environmental risk factors on both disease-free survival (DFS) and overall survival (OS) for adolescent and young adult cancer survivors.
Secondary Objectives:
1. To establish the associations of individual resilience factors on DFS and OS for adolescent and young adult cancer survivors.
2. To establish the associations of social-environmental risk factors and individual resilience factors on quality of life (QOL) for adolescent and young adult cancer survivors.
3. To quantify the extent to which alterations in human gene expression could potentially mediate the effects of social-environmental risk factors and individual resilience factors on DFS, and OS for adolescent and young adult cancer survivors.
Exploratory Objective:
1. To determine whether the relationship between social-environmental risk factors or individual resilience factors and distal outcomes may be moderated by race/ethnicity, sex and gender identity, and geography for adolescent and young adult cancer survivors.
Non-Hodgkin's Lymphoma
- Rutgers Cancer Institute of New Jersey
Inclusion Criteria
- Patient must be >= 18 years of age at the time of registration
- Patient must have been between the ages of 15-39 at the time of their first primary
cancer diagnosis of Hodgkin lymphoma or non-Hodgkin lymphoma (NHL)
- Patient must have completed therapy (with a complete response, per clinician
determination) at the time of registration
- Patients last date of prior systemic therapy for first primary diagnosis for Hodgkin
lymphoma or non-Hodgkin lymphoma must have been within one year prior to
registration
- NOTE: Systemic therapy refers to all anti-cancer therapy, including but not
limited to chemotherapy, intravenous (IV) or oral targeted medications, or
radiation, and administered via a clinical trial or standard approach
- Patient must have an Eastern Cooperative Oncology Group (ECOG) Performance Status of
0-3
- Patient must be English speaking in order to be able to complete the required QOL
forms on this study
- NOTE: Sites cannot translate the associated QOL forms
- Patient must not be receiving active therapy for Hodgkin lymphoma or non-Hodgkin
lymphoma
- Patient must have internet access through computer, tablet, or smartphone
- Patient must have email address
- Patient must have the ability to understand and the willingness to sign a written
informed consent document. Patients with impaired decision-making capacity (IDMC)
who have a legally authorized representative (LAR) or caregiver and/or family member
available will also be considered eligible
Please note that we have obtained the inclusion and exclusion criteria information from the National Institutes of Health’s clinical trials web site ClinicalTrials.gov. The listed criteria may not necessarily reflect recent amendments to the protocol and the current criteria.
For further information about clinical trials, please contact us at 732-235-7356.