OCTANE: Adjuvant Liposomal Doxorubicin and Carboplatin for Early-Stage Triple-Negative Breast Cancer.

Inclusion Criteria: - Newly diagnosed early stage triple negative breast cancer (TNBC) with a primary tumor size less than 2.5cm and nodal disease of N0/N1mi on final surgical pathology. - Patients who have completed primary surgical treatment. - Estrogen receptor (ER) expression of 20% or less, progesterone receptor (PgR) expression of 20% or less, and human epidermal growth factor receptor 2 (HER2) status 0-2+ by immunohistochemistry (IHC) or fluorescence in situ hybridization (FISH) result of 2.0 or less. - Participants with a history of prior cancers are allowed if there is no evidence of disease within the last five years. - Eastern Cooperative Oncology Group (ECOG) performance status of 0-1. - Baseline left ventricular ejection fraction (LVEF) greater than 50% (most recent measurement within the last 5 years). - No prior history of treatment with anthracycline-based chemotherapy. - Adequate bone marrow function: - Absolute neutrophil count (ANC) greater than or equal to 1500/uL. - Platelet count greater than or equal to 100,000/uL. - Hemoglobin level greater than or equal to 9.0 g/dL. - Adequate hepatic function: - Total bilirubin less than or equal to 1.5 times the upper limit of normal (ULN). - Aspartate aminotransferase (AST) levels (also known as serum glutamic-oxaloacetic transaminase, SGOT) less than or equal to 5 times the ULN. - Alanine aminotransferase (ALT) levels (also known as serum glutamic-pyruvic transaminase, SGPT) less than or equal to five times the ULN. - Participants with biliary obstruction must have restored biliary flow through the placement of an endoscopic common bile duct stent or percutaneous drainage. - Adequate renal function, with a creatinine level less than 1.5 times the institutional ULN or a calculated creatinine clearance greater than or equal to 50 mL/min using the Cockcroft-Gault formula. - Ability to understand the nature of the study protocol and provide written informed consent. - Willingness and ability to comply with scheduled visits and treatment plans. Exclusion Criteria: - Participants with stage III-IV breast cancer. - Uncontrolled hypertension, defined as systolic blood pressure greater than 190 mm Hg or diastolic blood pressure greater than 100 mm Hg. - Active liver disease. - Any condition, including the presence of laboratory abnormalities that, in the investigator's opinion, would place the participant at an unacceptable risk if they were to participate in the study. - Pre-existing sensory neuropathy greater than grade 1. - Clinically significant cardiac disease, such as congestive heart failure, symptomatic coronary artery disease, and uncontrolled cardiac arrhythmias, or a history of myocardial infarction within the last six months. - Presence of a serious non-healing wound, ulcer, or bone fracture. - Participants with uncontrolled and/or active infection with HIV, Hepatitis B, or Hepatitis C. - Participants with a history of allergy or hypersensitivity to any of the study drugs. - Any significant medical condition, laboratory abnormality, or psychiatric illness that would prevent the participant from participating in the study.