Ploss A.*, Evans M.J.*, Gaysinskaya A., Panis M., You H., de Jong Y.P., Rice C.M. (2009) Human occludin is a hepatitis C virus entry factor required for infection of mouse cells, Nature, 457: 882-6. PMC2762424
Dorner, M., Horwitz, J.A., Robbins, J., Barry, W.T., Mu, K., Jones, C.T., Schoggins, Catanese, M.T., J.W., Burton, D.R., Law, M., Rice, C.M., Ploss, A. (2011) A genetically humanized mouse model for hepatitis C virus infection, Nature, 474: 209-211. PMC3159410
Klein F., Halper-Stromberg A., Horwitz J.A., Gruell H., Scheid J.F., Bournazos S., Mouquet H., Spatz L.A., Diskin R., Abadir A., Dorner M., Billerbeck E., Labitt R.N., Gaebler C., Marcovecchio P., Incesu R.B., Eisenreich T.R., Bieniasz P.D., Seaman M.S., Bjorkman P.J., Ravetch J.V., Ploss A., Nussenzweig M.C. (2012), HIV therapy by a combination of broadly neutralizing antibodies in humanized mice, Nature, 492: 118-22. PMC3809838
Dorner M., Horwitz J.A.*, Donovan B.M.*, Labitt R.N., Budell W.C., Friling T., Vogt A., Catanese M.T., Satoh T., Kawai T., Akira S., Law M., Rice C.M., Ploss A. (2013) Completion of the entire hepatitis C virus life-cycle in genetically humanized mice, Nature, 501(7466):237-41, PMCID:PMC3858853
de Jong, Y.P., Dorner, M., Mommersteeg, M.C., Xiao, J.W., Balazs, A.B., Robbins, J.B., Vega, K., Labitt, R.N., Donovan, B.M., Giang, E., Krishnan, A., Chiriboga, L., Charlton, M.R., Burton, D.R., Baltimore, D., Law, M., Rice, C.M., Ploss, A. (2014) Broadly neutralizing antibodies abrogate established hepatitis C virus infection, Science Translational Medicine, 6(254):254ra129, PMCID:PMC4312107
Douam, F., Gaska, J., Winer, B.Y., Ding, Q., von Schaewen, M., Ploss, A. (2015) Genetic dissection of the host tropism of human tropic pathogens, Annual Reviews in Genetics, 2015; 49:21-45. doi: 10.1146/annurev-genet-112414-054823. PMCID: PMC5075990
Ding, Q, Heller, B., Capucino, J.M.V., Song, B., Nimgaonkar, I., Hrebikova, G., Contreras, J.E, Ploss, A. (2017) Hepatitis E virus ORF3 is a functional ion channel required for release of infectious particles, Proc Natl Acad Sci U S A, 114(5):1147-1152. PMCID: PMC5293053
Douam, F., Hrebikova, G., Soto Albrecht, Y.E., Sellau, J., Sharon, Y., Ding, Q., Ploss, A. (2017) Single-cell tracking of flavivirus RNA uncovers species-specific interactions with the immune system dictating disease outcome. Nature Communications, 8:14781. doi: 10.1038/ncomms14781. PMCID:PMC5424064
Winer, B.Y., Huang, T.S., Pludwinski, E., Wojcik, F. Lipkowitz, G., Parekh, A., Cho, C., Shrirao, A., Muir, T., Novik, E., Ploss, A. (2017) Long-term persistent hepatitis B virus infection in a scalable micro-well primary hepatocyte coculture system, Nature Communications, PMCID:PMC5527081
Nimgaonkar, I., Ding, Q., Schwartz, R.E., Ploss, A. (2018) Hepatitis E virus: Advances and Challenges, Nature Reviews Hepatology & Gastroenterology, 15(2):96-110
Ding, Q., Gaska, J.M., Heller, B., Ploss, A. (2018) Species-specific disruption of the STING-dependent antiviral cellular defenses by the Zika virus NS2B3 protease, Proc Natl Acad Sci U S A. Pii: 201803406. doi: 10.1073/pnas.1803406115. PMID:29915078
Dragovic SM, Agunbiade TA, Freudzon M, Yang J, Hastings AK, Schleicher TR, Zhou X, Craft S, Chuang YM, Gonzalez F, Li Y, Hrebikova G, Tripathi A, Mlambo G, Almeras L, Ploss A, Dimopoulos G, Fikrig E (2018) Immunization with AgTRIO, a Protein in Anopheles Saliva, Contributes to Protection against Plasmodium Infection in Mice, Cell Host & Microbe, 23(4):523-535.e5, PMCID:PMC5998332
Winer, B.Y., Shirvani-Dastgerdi, E., Bram, Y., Sellau, J., Low, B.E., Johnson, H., Huang, T., Hrebikova, G., Heller, B., Sharon, Y., Giersch, J., Gerges, S., Seneca, K., Pais, M.A., Frankel, A.S., Lipkowitz, G., Chiriboga, L., Cullen, J., Nahass, R.G., Lutgehetmann, M., Toettcher, J.E., Wiles, M.V., Schwartz, R.E., Ploss, A. (2018) Preclinical assessment of antiviral combination therapy in a genetically humanized mouse model for persistent hepatitis delta virus infection, Science Translational Medicine, 10(447). Pii: eaap9328. doi: 10.1126/scitranslmed.aap9328.
Douam, F., Ziegler, C.G.K, Hrebikova, G., Fant, B., Leach, R., Parson, L., Wang, W., Gaska, J.M., Winer, B.Y., Heller, B., Shalek, A.K., Ploss, A. (2018) Selective expansion of myeloid and NK cells in humanized mice yields human-like host responses to vaccination, Nature Communications, 28;9(1):5031, PMCID:PMC6262001
Wei, L., Ploss, A. (2020) Core components of DNA lagging strand synthesis machinery are essential for the reconstitution of hepatitis B virus cccDNA formation, Nature Microbiology, doi: 10.1038/s41564-020-0678-0. [Epub ahead of print]
