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A Phase II Trial of Tislelizumab Consolidation after Liver-Directed Therapy for Hepatocellular Carcinoma.
Protocol: 072105Principal Investigator:
- Salma Jabbour
Applicable Disease Sites: Liver -
A Phase II Trial of Tislelizumab Consolidation after Liver-Directed Therapy for Hepatocellular Carcinoma.
Protocol: 072105Principal Investigator:
- Salma Jabbour
Applicable Disease Sites: Liver -
A Phase 3 Multicenter, Open-Label, Randomized,2-Arm Study of Adjuvant Daraxonrasib versus Standard of Care Observation Following Completion of Neoadjuvant and/or Adjuvant Chemotherapy in Patients with Resected Pancreatic Ductal Adenocarcinoma.
Protocol: 072601Principal Investigator:
- Prateek Gulhati
Applicable Disease Sites: Pancreas -
A Phase 3 Multicenter, Open-Label, Randomized,2-Arm Study of Adjuvant Daraxonrasib versus Standard of Care Observation Following Completion of Neoadjuvant and/or Adjuvant Chemotherapy in Patients with Resected Pancreatic Ductal Adenocarcinoma.
Protocol: 072601Principal Investigator:
- Prateek Gulhati
Applicable Disease Sites: Pancreas -
A Phase 3, Randomized, Double-blind, Placebo-controlled Study of Investigator Choice of Chemotherapy (modified FOLFIRINOX or Gemcitabine plus Nab-paclitaxel) with or without Zoldonrasib (RMC-9805) as First-line Treatment in Patients with Metastatic KRAS G12D-Mutated Pancreatic Adenocarcinoma.
Protocol: 072604Principal Investigator:
- Prateek Gulhati
Applicable Disease Sites: Colon -
A Phase 3, Randomized, Double-blind, Placebo-controlled Study of Investigator Choice of Chemotherapy (modified FOLFIRINOX or Gemcitabine plus Nab-paclitaxel) with or without Zoldonrasib (RMC-9805) as First-line Treatment in Patients with Metastatic KRAS G12D-Mutated Pancreatic Adenocarcinoma.
Protocol: 072604Principal Investigator:
- Prateek Gulhati
Applicable Disease Sites: Colon -
An Integrated Phase 2/3 and Phase 3 Trial of MRD-Based Optimization of Adjuvant Therapy in Urothelial Cancer.
Protocol: 082401Principal Investigator:
- Biren Saraiya
Applicable Disease Sites: Urinary Bladder -
A Phase 1, Multiple-Dose Study to Evaluate the Safety and Tolerability of XmAb®819 in Subjects with Relapsed or Refractory Clear Cell Renal Cell Carcinoma.
Protocol: 082409Principal Investigator:
- Biren Saraiya
Applicable Disease Sites: Kidney -
An Integrated Phase 2/3 and Phase 3 Trial of MRD-Based Optimization of Adjuvant Therapy in Urothelial Cancer.
Protocol: 082401Principal Investigator:
- Biren Saraiya
Applicable Disease Sites: Urinary Bladder -
A Phase 1, Multiple-Dose Study to Evaluate the Safety and Tolerability of XmAb®819 in Subjects with Relapsed or Refractory Clear Cell Renal Cell Carcinoma.
Protocol: 082409Principal Investigator:
- Biren Saraiya
Applicable Disease Sites: Kidney -
A032201: Short TeRm Intensified Pembrolizumab (KEytruda) and Tivozanib for High-risk renal cell carcinoma STRIKE
Protocol: 082502Principal Investigator:
- Biren Saraiya
Applicable Disease Sites: Kidney -
A032201: Short TeRm Intensified Pembrolizumab (KEytruda) and Tivozanib for High-risk renal cell carcinoma STRIKE
Protocol: 082502Principal Investigator:
- Biren Saraiya
Applicable Disease Sites: Kidney -
A Phase 3, Single-arm, Multicenter Study to Evaluate the Efficacy and Safety
of UGN-104, a Novel Formulation of UGN-101, for the Treatment of Patients With Low-grade Upper Tract Urothelial Cancer (LG-UTUC)
Protocol: 082508Principal Investigator:
- Saum Ghodoussipour
Applicable Disease Sites: Other Urinary -
A Phase 3, Single-arm, Multicenter Study to Evaluate the Efficacy and Safety
of UGN-104, a Novel Formulation of UGN-101, for the Treatment of Patients With Low-grade Upper Tract Urothelial Cancer (LG-UTUC)
Protocol: 082508Principal Investigator:
- Saum Ghodoussipour
Applicable Disease Sites: Other Urinary -
A Randomized, Double-Blind, Active-Control, Multicenter Phase 3 Trial of
Casdatifan and Cabozantinib Versus Placebo and Cabozantinib in Patients
With Advanced Clear Cell Renal Cell Carcinoma
Protocol: 082510Principal Investigator:
- Biren Saraiya
Applicable Disease Sites: Kidney -
A Randomized, Double-Blind, Active-Control, Multicenter Phase 3 Trial of
Casdatifan and Cabozantinib Versus Placebo and Cabozantinib in Patients
With Advanced Clear Cell Renal Cell Carcinoma
Protocol: 082510Principal Investigator:
- Biren Saraiya
Applicable Disease Sites: Kidney