Positions Available

Postdoctoral positions are available under the mentorship of Dr. Cristina Montagna in the Division of Radiation Cancer Biology at the Department of Radiation Oncology, to study mechanisms of genomic instability in mammalian systems. Projects focus on the contribution of genomic instability in the form of aneuploidies, single-nucleotide variants (SNVs) and small insertions and deletions (INDELs) to early transformation and progression to tumorigenesis.

Research Overview

Research in the Montagna Laboratory at the Rutgers Cancer Institute aims to understand the mechanisms by which genomic instability promotes tumor initiation and progression. Using advanced molecular cytogenetic approaches and single cell genomics methodologies applied to human and murine in culture and in vivo models we investigate the roles of large copy number alterations and papilloma virus insertional mutagenesis to tumor initiation and progression.

• ANDRIANI, G. A., ALMEIDA, V. P., FAGGIOLI, F., MAURO, M., TSAI, W. L., SANTAMBROGIO, L., MASLOV, A., GADINA, M., CAMPISI, J., VIJG, J. & MONTAGNA, C. 2016a. Whole Chromosome Instability induces senescence and promotes SASP. Sci Rep, 6, 35218.
• ANDRIANI, G. A., FAGGIOLI, F., BAKER, D., DOLLE, M. E., SELLERS, R. S., HEBERT, J. M., VAN STEEG, H., HOEIJMAKERS, J., VIJG, J. & MONTAGNA, C. 2016b.

Dr. Cristina Montagna a cancer biologist with extensive expertise in molecular cytogenetic and cell biology. Her laboratory has contributed significant work to the field of oncogene discovery, genomic instability in cancer, and age-related tissue degeneration. She obtained her PhD from the University of Milano where she trained with Prof.